Wellcome Trust Sanger Institute

The Wellcome Trust Sanger Institute (previously known as ‘The Sanger Centre’) is a non-profit, British genomics and genetics research institute, primarily funded by the Wellcome Trust.

The first ever vaccine target for a family of parasites that cause devastating disease in millions of animals and humans has been discovered

Could a new malaria discovery offer effective treatment for a range of infectious diseases including COVID-19?

DNA fingerprints could catch cancer-causing culprits

Tailor-made vaccines could cut the rates of serious bacterial diseases in half

Boosting research into development and regenerative medicine with a major stem cell discovery

Expanded Potential Stem Cell lines of pig and human cells established A new approach has enabled researchers to create Expanded Potential Stem Cells (EPSCs) of both pig and human cells. These stem cells have the features of the very first cells in the developing embryo, and can develop into any type of cell. The research

Boosting research into development and regenerative medicine with a major stem cell discovery

A promising new treatment for acute myeloid leukaemia

Ingredient in pre-clinical treatment for retinal neovascular disease targets gene associated with acute myeloid leukaemia An active ingredient in eye drops that were being developed for the treatment of a form of eye disease has shown promise for treating an aggressive form of blood cancer. Scientists at the Wellcome Sanger Institute, University of Cambridge, University

A promising new treatment for acute myeloid leukaemia

A prediction tool for gene editing

Prediction resource could make CRISPR-Cas9 editing more reliable The largest study of CRISPR action to date has developed a method to predict the exact mutations CRISPR-Cas9 gene editing can introduce to a cell. Researchers at the Wellcome Sanger Institute edited 40,000 different pieces of DNA and analysed a thousand million resulting DNA sequences to reveal

A prediction tool for gene editing

Novel genes for osteoarthritis have been discovered that could lead to targeted therapies

The results could open the door to new targeted therapies for this debilitating disease in the future In the largest study of its kind, nine novel genes for osteoarthritis have been discovered by scientists from the Wellcome Sanger Institute and their collaborators. Results of the study, published today (19 March) in Nature Genetics, could open the door

Novel genes for osteoarthritis have been discovered that could lead to targeted therapies

Microreact, a free, real-time epidemic visualisation and tracking platform that has been used to monitor outbreaks of Ebola, Zika and antibiotic-resistant microbes

Researchers from the Wellcome Trust Sanger Institute and Imperial College London have developed Microreact, a free, real-time epidemic visualisation and tracking platform that has been used to monitor outbreaks of Ebola, Zika and antibiotic-resistant microbes. The team have collaborated with the Microbiology Society to allow any researcher around the world to share their latest information

Microreact, a free, real-time epidemic visualisation and tracking platform that has been used to monitor outbreaks of Ebola, Zika and antibiotic-resistant microbes

Bugs as drugs have the guts

Harnessing novel gut bacteria for human health Scientists at the Wellcome Trust Sanger Institute have grown and catalogued more than 130 bacteria from the human intestine according to a study published in Nature today (Wednesday May 4, 2016). The researchers have developed a process to grow the majority of bacteria from the gut, which will

Bugs as drugs have the guts

3-D ‘organoids’ grown from patient tumors could personalize drug screening

Three-dimensional cultures (or “organoids”) derived from the tumors of cancer patients closely replicate key properties of the original tumors, reveals a study published May 7 in Cell. These “organoid” cultures are amenable to large-scale drug screens for the detection of genetic changes associated with drug sensitivity and pave the way for personalized treatment approaches that

3-D ‘organoids’ grown from patient tumors could personalize drug screening

UEA research could revolutionise genomic sequencing of drug-resistant bacteria

New nanopore DNA sequencing technology on a device the size of a USB stick could be used to diagnose infection – according to new research from the University of East Anglia and Public Health England. Researchers tested the new technology with a complex problem – determining the cause of antibiotic resistance in a new multi-drug

UEA research could revolutionise genomic sequencing of drug-resistant bacteria

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Wellcome Trust Sanger Institute Research

Water vole genome will help boost conservation of one of UK's most endangered mammals
on June 24, 2021 at 3:23 am
The genome was generated by scientists at the Wellcome Sanger Institute, in collaboration with animal conservation charity the Wildwood Trust, as part of the Darwin Tree of Life Project.
Genetics ‘a new tool to help boost water vole conservation’
on June 24, 2021 at 2:39 am
Researchers at the Wellcome ... Research and are available to researchers and conservationists looking to better manage reintroduction efforts. Professor Mark Blaxter, of the Wellcome Sanger ...
Genetics ‘a new tool to help boost water vole conservation’
on June 24, 2021 at 2:15 am
Genetics could be used as a new tool to help boost water vole conservation in the UK, after scientists analysed the DNA of one of the country’s most threatened mammals. Researchers at the Wellcome ...
Water vole genome will help boost conservation of one of UK's most endangered mammals
on June 24, 2021 at 2:02 am
The genome, published today (24 June 2021) through Wellcome Open Research ... Trust in Kent, UK. DNA was extracted from this sample and sequenced by scientists at the Wellcome Sanger Institute ...
New tool can help conserve one of the UK’s most threatened mammals
on June 23, 2021 at 11:30 pm
The genome, published today (24 June 2021) through Wellcome Open Research ... Trust in Kent, UK. DNA was extracted from this sample and sequenced by scientists at the Wellcome Sanger Institute ...

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Wellcome Trust Sanger Institute Research

Advanced Research Assistant - Nature.com
June 27, 2021
Cellular signatures of kidney tumours discovered - EurekAlert
June 23, 2021
Water vole genome will help boost conservation of one of UK's most endangered mammals - Science Daily
June 24, 2021
Genetics 'a new tool to help boost water vole conservation' - Belfast Telegraph
June 24, 2021
UK at the forefront of genomics research - Scientific Computing World
June 18, 2021

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Wellcome Trust Sanger Institute Discovery

Africa: Discovery to Boost Malaria Treatment
on June 29, 2021 at 12:03 pm
Africa's malaria control strategy is to advance following a new study. The study by the Kenya Medical Research Institute (Kemri) Wellcome Trust Research Programme comes as Kenya seeks an alternative ...
Scientists Sequence Genome of European Water Vole
on June 24, 2021 at 12:40 pm
program lead for the Darwin Tree of Life project at the Wellcome Sanger Institute. The European water vole’s genome was sequenced from a single male collected from the Wildwood Trust ...
Genetics ‘a new tool to help boost water vole conservation’
on June 24, 2021 at 2:15 am
Genetics could be used as a new tool to help boost water vole conservation in the UK, after scientists analysed the DNA of one of the country’s most threatened mammals. Researchers at the Wellcome ...
New tool can help conserve one of the UK’s most threatened mammals
on June 23, 2021 at 11:30 pm
The genome was generated by scientists at the Wellcome Sanger Institute, in collaboration with animal conservation charity the Wildwood Trust, as part of the Darwin Tree of Life Project.
Structural biologists granted Wellcome Trust Investigator Awards
on June 23, 2021 at 9:00 pm
A pair of Leicester researchers studying the molecular machinery that controls gene expression have been awarded £3.89 million in research funding by the Wellcome Trust.