Washington University School of Medicine (WUSM)

Washington University School of Medicine (WUSM), located in St. Louis, Missouri, is the medical school of Washington University in St. Louis on the eastern border of Forest Park in St. Louis

A single treatment of laughing gas for treatment-resistant depression has rapid and lasting antidepressant effects

An antidepressant drug repurposed for patients with Covid-19 may prevent serious illness

Experts propose decentralized system to monitor wildlife markets, other hotspots

Gene therapy could be a new treatment approach for osteoarthritis and obesity

Major progress on identify Alzheimer’s before symptoms arise

When combined with age and genetic risk factor, test is 94% accurate Up to two decades before people develop the characteristic memory loss and confusion of Alzheimer’s disease, damaging clumps of protein start to build up in their brains. Now, a blood test to detect such early brain changes has moved one step closer to

Major progress on identify Alzheimer’s before symptoms arise

Could immunotherapy be effective against pancreatic cancer?

Chemical compound extends survival by months, in mice Pancreatic cancer is especially challenging to treat – only eight percent of patients are still alive five years after diagnosis. Chemotherapy and radiation therapy are of limited benefit, and even immunotherapy – which revolutionized treatment for other kinds of cancer by activating the body’s immune system to

Could immunotherapy be effective against pancreatic cancer?

Aging delayed . . . in mice for now

An enzyme in blood of young mice extends life span New research has identified a novel approach to staving off the detrimental effects of aging, according to a study from Washington University School of Medicine in St. Louis. The study suggests that a protein that is abundant in the blood of young mice plays a

Aging delayed . . . in mice for now

Can drug resistance in tuberculosis be reversed?

About 1.5 million people died of tuberculosis (TB) in 2017, making it the most lethal infectious disease worldwide. A growing rise in drug-resistant TB is a major obstacle to successfully treating the illness. Now, researchers at Washington University School of Medicine in St. Louis and Umea University in Sweden have found a compound that prevents

Can drug resistance in tuberculosis be reversed?

Cavitation dose painting would allow precise delivery of a certain amount of drugs to an exact location

Researchers are integrating ultrasound imaging with ultrasound therapy to pave the way for a new kind of drug delivery If traditional drug delivery were a type of painting, it might be akin to paintball. With good aim, a majority of the paint ends on the bullseye, but it also drips and splashes, carrying streams of

Cavitation dose painting would allow precise delivery of a certain amount of drugs to an exact location

Detecting Alzheimer’s damage before symptoms appear using a new blood test

Test also may identify neurodegeneration in other brain diseases, injuries A simple blood test reliably detects signs of brain damage in people on the path to developing Alzheimer’s disease – even before they show signs of confusion and memory loss, according to a new study from Washington University School of Medicine in St. Louis and

Detecting Alzheimer’s damage before symptoms appear using a new blood test

Curtailing the spread of antibiotic resistance

Study identifies key step in spread of drug resistance, opportunity for intervention Spotless surfaces in hospitals can hide bacteria that rarely cause problems for healthy people but pose a serious threat to people with weakened immune systems. Acinetobacter baumannii causes life-threatening lung and bloodstream infections in hospitalized people. Such infections are among the most difficult to treat

Curtailing the spread of antibiotic resistance

Using biointegrated LEDs to stimulate nerves

A team of neuroscientists and engineers has developed a tiny, implantable device that has potential to help people with bladder problems bypass the need for medication or electronic stimulators. The team — from Washington University School of Medicine in St. Louis, the University of Illinois at Urbana-Champaign, and the Feinberg School of Medicine at Northwestern

Using biointegrated LEDs to stimulate nerves

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Washington University School of Medicine (WUSM) Research

Children not at increased risk of higher viral load compared to adults with COVID-19 infection: StudyThe
on June 20, 2021 at 9:15 pm
The role of children in community SARS-CoV-2 transmission remains poorly understood as most children with SARS-CoV-2 infection are asymptomatic or experience mild disease and also there is ...
Tarantula Toxin Attacks With Molecular Stinger – May Hold Answers to Better Control of Chronic Pain
on June 20, 2021 at 2:31 am
Venom immobilizes prey by interfering with sodium channels that generate electrical signals in the animal's nerve cells. Oversized, hairy tarantulas may be unsightly and venomous, but surprisingly ...
Washington state led much of the nation in seizing guns to prevent violence. How's the law working?
on June 19, 2021 at 6:00 am
Washington state has a law to remove guns from peoples' possession and prevent them from purchasing or having access to new firearms for one year.
New Wash U initiative aims to decrease outbreaks, promote vaccine literacy in underserved school districts
on June 17, 2021 at 5:13 pm
For months, desks in schools across St. Louis sat empty and now teachers, parents and doctors are preparing for a safe return to in-person learning this fall.
Columbia School of Nursing launches LGBT health research program
on June 17, 2021 at 7:56 am
The Columbia University School of Nursing announced Tuesday that it has established the Center for Sexual and Gender Minority Health Research to address disparities among the LGBT community. The ...

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Washington University School of Medicine (WUSM) Research

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Washington University School of Medicine (WUSM) Discovery

Tarantula Toxin Attacks With Molecular Stinger – May Hold Answers to Better Control of Chronic Pain
on June 20, 2021 at 2:31 am
Venom immobilizes prey by interfering with sodium channels that generate electrical signals in the animal's nerve cells. Oversized, hairy tarantulas may be unsightly and venomous, but surprisingly ...
The quest for a pill to fight viruses gets a $3.2 billion boost
on June 17, 2021 at 2:33 pm
The Biden administration will invest $3.2 billion to find new antiviral drugs, modeling the investment after the one that helped stimulate development of drugs that transformed HIV.
Immune system protein may defend against deadly intestinal disease in babies
on June 16, 2021 at 10:18 am
The intestinal disease necrotizing enterocolitis is a leading cause of death among premature infants born in the U.S. and across the globe.
An unmarked gravesite drags a not-so-distant horror back into the spotlight. Is this a real reckoning?
on June 16, 2021 at 4:59 am
The discovery of an unmarked burial site containing the remains of 215 children at the former Kamloops Residential School in British ... Ryerson University sociologist Eva Jewell, a member of ...
When genocide hits home: My hometown was an integral part of Canada’s attempt at cultural erasure
on June 14, 2021 at 1:32 pm
The discovery of the remains of 215 children in the grounds of the Kamloops Indian Reservation School in western Canada confirmed what that country’s Truth and Reconciliation Commission had concluded: ...