Broad Institute

The Eli and Edythe L. Broad Institute of MIT and Harvard, often referred to as the Broad Institute, is a biomedical and genomic research center located in Cambridge, Massachusetts, United States.

Predictive, preventive, personalized and participatory medicine, known as P4, gets a big privacy and security boost from cryptography

Synthetic microbial spores can be safely introduced onto objects and surfaces for tracking purposes

CRISPR can be a conservation and resource management tool to help endangered species

AI identifies a powerful new drug that can kill many species of antibiotic-resistant bacteria

DNA fingerprints could catch cancer-causing culprits

New tricks for many old drugs to kill cancer cells

Search-and-replace genome editing

Prime editing system offers wide range of versatility in human cells, correcting disease-causing genetic variations A team from the Broad Institute of MIT and Harvard has developed a new CRISPR genome-editing approach that has the potential to correct up to 89 percent of known disease-causing genetic variations. Researchers have combined two of the most important proteins

Search-and-replace genome editing

Adding new and key capabilities to gene-editing technology are a big step

A team led by researchers from Broad Institute of MIT and Harvard, and the McGovern Institute for Brain Research at MIT, has characterized and engineered a new gene-editing system that can precisely and efficiently insert large DNA sequences into a genome. The system, harnessed from cyanobacteria and called CRISPR-associated transposase (CAST), allows efficient introduction of DNA while

Adding new and key capabilities to gene-editing technology are a big step

Synthetic biologists have added high-precision analog-to-digital signal processing to the genetic circuitry of living cells

Synthetic biologists add tunable, analog-to-digital converter to their toolkit Synthetic biologists have added high-precision analog-to-digital signal processing to the genetic circuitry of living cells. The research, described online today in the journal Science, dramatically expands the chemical, physical and environmental cues engineers can use to prompt programmed responses from engineered organisms. Using a biochemical process called cooperative

Synthetic biologists have added high-precision analog-to-digital signal processing to the genetic circuitry of living cells

An important new disease surveillance tool can detect any human virus to help disease outbreak monitoring

Computational method helps scientists examine microbes at a larger, more comprehensive scale than previously possible During the Zika virus outbreak of 2015–16, public health officials scrambled to contain the epidemic and curb the pathogen’s devastating effects on pregnant women. At the same time, scientists around the globe tried to understand the genetics of this mysterious

An important new disease surveillance tool can detect any human virus to help disease outbreak monitoring

Could a newly identified cell type lead to the cure for cystic fibrosis and more?

These cells appear to be the primary source of activity of the gene responsible for multiorgan disease n separate studies published online today in Nature, two independent research teams report the discovery of a new, rare type of cell in the human airway. These cells appear to be the primary source of activity of the CFTR gene, mutations

Could a newly identified cell type lead to the cure for cystic fibrosis and more?

A strip of paper can now indicate presence of pathogens, tumor DNA, or any genetic disease signature of interest

A strip of paper can now indicate presence of pathogens, tumor DNA, or any genetic signature of interest. 100-fold greater sensitivity, the ability to detect multiple targets at once, and other new features further enhance SHERLOCK’s power for detecting genetic signatures. The team that first unveiled the rapid, inexpensive, highly sensitive CRISPR-based diagnostic tool called SHERLOCK has

A strip of paper can now indicate presence of pathogens, tumor DNA, or any genetic disease signature of interest

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Broad Institute Research

5 for Good: Local women raise awareness, research rare fatal illness
Extending healthy life, rather than extending illness." Since prion disease is rare, Vallabh said it’s challenging to secure research funding, but the Prion Alliance has received grant money raised in ...
René Salazar joins Broad Institute as Chief Equity Officer
René Salazar, former assistant dean for diversity and professor of internal medicine and medical education at the University of Texas at Austin Dell Medical School, has joined the Broad Institute of ...
Twist Bioscience and the Broad Institute Create Custom Whole Exome Target Enrichment Panel for Clinical Research
Twist Bioscience Corporation (NASDAQ: TWST), a company enabling customers to succeed through its offering of high-quality synthetic DNA using its silicon platform, today announced an agreement with ...
Broad Institute, Intel, Google collaborate to Advance Biomedical Research
The Broad Institute enables new levels of research with Google engineering and Intel optimizations. These days scientists and researchers rely on strong computational horsepower to overcome challenges ...
Broad Institute taps Google Cloud to power genomic research platform
Cambridge, Mass.-based Harvard University and Cambridge-based Massachusetts Institute of Technology's Broad Institute are partnering and moving their workloads to Google Cloud to enhance research ...

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Broad Institute Research

Broad Institute taps Google Cloud to power genomic research platform - Becker's Hospital Review
October 12, 2021
Broad Institute hires René Salazar to tackle biomedical research's diversity problem - Endpoints News
October 14, 2021
Richard Merkin, MD, renews support for transformative science at Broad Institute - PRNewswire
October 6, 2021
Twist Bioscience and the Broad Institute Create Custom Whole Exome Target Enrichment Panel for Clinical Research - Business Wire
October 13, 2021
Broad Institute, Intel, Google collaborate to Advance Biomedical Research - TechnoSports
October 13, 2021

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Broad Institute Discovery

Discovery Points Toward the Next Revolution in Genome Editing Technology
New Programmable Gene Editing Proteins Found Outside of CRISPR Systems Researchers find RNA-guided enzymes are more diverse and widespread than previously believed. Within the last decade, scientists ...
Terasaki Institute for Biomedical Innovation Signs Agreement with Qatar Foundation
The Terasaki Institute for Biomedical Innovation (TIBI) has recently signed an agreement with Qatar Foundation. Qatar Foundation is comprised of over 50 entities and is a non-profit organization that ...
Epicore Biosystems Launches Discovery Patch® Sweat Collection System
The Discovery Patch® Sweat Collection System is designated to be used by clinicians to track sweat biomarkers and sweat dynamics in the healthcare setting.
PerkinElmer, Inc.: PerkinElmer Supports JUMP-CP Consortium Creating World's Largest, Public Cell Painting Dataset
Leading academic, research and industry group led by Broad Institute to help speed drug discovery PerkinElmer, Inc., a global leader committed to innovating for a healthier world, today announced ...
Artios Doses First Patient in Phase 1/2a Study of Polθ Inhibitor ART4215
Hamilton, M.D., Director of the Breast Cancer and Gynecologic Cancer Research Program, Sarah Cannon Research Institute at Tennessee ... that ART4215 has broad potential clinical utility, as ...