Broad Institute

The Eli and Edythe L. Broad Institute of MIT and Harvard, often referred to as the Broad Institute, is a biomedical and genomic research center located in Cambridge, Massachusetts, United States.

New method can edit genes associated with high cholesterol and partially restore vision in mice

Opening genomics data to all with a new cloud-based platform

Predictive, preventive, personalized and participatory medicine, known as P4, gets a big privacy and security boost from cryptography

Synthetic microbial spores can be safely introduced onto objects and surfaces for tracking purposes

CRISPR can be a conservation and resource management tool to help endangered species

AI identifies a powerful new drug that can kill many species of antibiotic-resistant bacteria

DNA fingerprints could catch cancer-causing culprits

New tricks for many old drugs to kill cancer cells

Search-and-replace genome editing

Prime editing system offers wide range of versatility in human cells, correcting disease-causing genetic variations A team from the Broad Institute of MIT and Harvard has developed a new CRISPR genome-editing approach that has the potential to correct up to 89 percent of known disease-causing genetic variations. Researchers have combined two of the most important proteins

Search-and-replace genome editing

Adding new and key capabilities to gene-editing technology are a big step

A team led by researchers from Broad Institute of MIT and Harvard, and the McGovern Institute for Brain Research at MIT, has characterized and engineered a new gene-editing system that can precisely and efficiently insert large DNA sequences into a genome. The system, harnessed from cyanobacteria and called CRISPR-associated transposase (CAST), allows efficient introduction of DNA while

Adding new and key capabilities to gene-editing technology are a big step

Synthetic biologists have added high-precision analog-to-digital signal processing to the genetic circuitry of living cells

Synthetic biologists add tunable, analog-to-digital converter to their toolkit Synthetic biologists have added high-precision analog-to-digital signal processing to the genetic circuitry of living cells. The research, described online today in the journal Science, dramatically expands the chemical, physical and environmental cues engineers can use to prompt programmed responses from engineered organisms. Using a biochemical process called cooperative

Synthetic biologists have added high-precision analog-to-digital signal processing to the genetic circuitry of living cells

An important new disease surveillance tool can detect any human virus to help disease outbreak monitoring

Computational method helps scientists examine microbes at a larger, more comprehensive scale than previously possible During the Zika virus outbreak of 2015–16, public health officials scrambled to contain the epidemic and curb the pathogen’s devastating effects on pregnant women. At the same time, scientists around the globe tried to understand the genetics of this mysterious

An important new disease surveillance tool can detect any human virus to help disease outbreak monitoring

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Broad Institute Research

The Petri Dish: Departed White House adviser returns to the Broad
Eric Lander, who was the founding director of the Broad Institute of MIT and Harvard, is set to return to the research organization a year after leaving a top post at the White House. Lander had been ...
Broad Street Run: When is it? When does registration open?
Changes to the Broad Street Run this year: What you need to know Changes to the Broad Street Run this year: What you need to know 01:58 PHILADELPHIA (CBS) -- Ready, set, go! The 2023 Independence ...
China'a research institute uses US computer chips despite restrictions
China's nuclear weapons research institute managed to buy the United States chips at ... with many bought by the institute's laboratory studying computational fluid dynamics, a broad scientific field ...
Broad Range Antibodies Neutralize All SARS-CoV-2 Variants and Other Coronaviruses
Coldspot-guided method identified antibodies against highly conserved SARS-CoV-2 epitopes that recognize all variants and other coronaviruses.
Rutgers Powers Up for Offshore Wind Energy Research
Rutgers researchers recently shared their expertise in offshore wind energy with each other and those expected to play a key role in New Jersey’s effort to help the nation fight global warming by ...

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Broad Institute Discovery

FBI: How Householder overpowered dissenters with FirstEnergy’s money to pass HB6
Ohio House Speaker Larry Householder and his allies used the utility’s money to anonymously support the bill’s backers and punish its dissenters at the same time. FirstEnergy never disclosed that it ...
What China wanted out of Blinken's now postponed visit
While U.S. officials had hoped to establish guardrails to prevent tensions from spiraling into conflict, Beijing wants to reset the relationship on the basis of broad principles that would make issues ...
The Top 10 Best Movies About First Contact With Aliens
As scientists watch the skies for signs of alien life, cinema imagines what it will be like when we finally find it.
Drug Discovery & Development
This unique program provides the rigorous scientific and technical training necessary to succeed in the complex and multidisciplinary field of drug discovery and introduces students to a broad array ...
Predictive Discovery hails broad results up to 38.2 metres at 5.28 g/t gold from Bankan in Guinea
Predictive Discovery Ltd (ASX:PDI) continues to demonstrate the golden potential of the Bankan Project in Guinea with more successful infill drilling, unearthing large intersections of high-grade gold ...