Brigham and Women’s Hospital

Brigham and Women’s Hospital (BWH, “The Brigham”) is the largest hospital of the Longwood Medical and Academic Area in Boston, Massachusetts, USA.

Could a self-injecting pill deliver results comparable to standard injections?

Are patients receptive to interacting with robots designed to evaluate symptoms in a contact-free way?

Treating musculoskeletal injuries with a handheld 3D bioprinter

Using light to help break down ingestible medical devices

Developing a once-a-month oral contraceptive

Investigators designed a capsule that can be swallowed once a month, reside in the stomach and release a drug to prevent pregnancy Daily oral contraceptive pills allow women to manage their fertility, but this method of contraception relies on a user remembering to take her pill at the same time every day. In a multi-national

Developing a once-a-month oral contraceptive

Delivering insulin, therapeutics and perhaps even vaccines . . . by pill

Coated pill carries microneedles that deliver insulin and other drugs to the lining of the small intestine. Many drugs, especially those made of proteins, cannot be taken orally because they are broken down in the gastrointestinal tract before they can take effect. One example is insulin, which patients with diabetes have to inject daily or

Delivering insulin, therapeutics and perhaps even vaccines . . . by pill

Machine learning can help predict the risk of heart failure in diabetes patients

Investigators used artificial intelligence to identify top 10 variables that can predict, with a high degree of accuracy, future heart failure among patients living with diabetes Heart failure is an important potential complication of type 2 diabetes that occurs frequently and can lead to death or disability. Earlier this month, late-breaking trial results revealed that

Machine learning can help predict the risk of heart failure in diabetes patients

Can gut bacteria prevent and even reverse food allergies?

Study finds altered gut microbiota in infants with food allergy; oral therapy to replenish bacteria prevented food allergy and suppressed established disease in mice. Every three minutes, a food-related allergic reaction sends someone to the emergency room in the U.S. Currently, the only way to prevent a reaction is for people with food allergies to

Can gut bacteria prevent and even reverse food allergies?

Using sensory nanoparticles to detect disease

Building on new insights about nanoparticles, investigators develop a test for early detection of diseases, including different types of cancer Investigators from Brigham and Women’s Hospital are taking advantage of a unique phenomenon of nanoparticles to develop a test for early detection of different types of diseases, including cancer. Through previous investigations, Morteza Mahmoudi, PhD,

Using sensory nanoparticles to detect disease

Researchers invent a resistance-sensing injection device (needle) that knows where to go

Smart Needle Syringes and hollow needles—among the most feared and most commonly used tools in medical practice—have been around for more than a century. However, the precise insertion of these devices depends largely on the technique and skill of the person delivering the injection. And some anatomical regions, such as the space in the back

Researchers invent a resistance-sensing injection device (needle) that knows where to go

A big move forward towards defeating glioblastoma

New approach using multiple microRNA ‘hitchhikers’ to weaken cancer cells in advance of standard therapy shows promise in preclinical models In cancer therapeutics research, microRNAs–tiny strings of nucleotides that get churned out inside cells–have been a source of both excitement and disappointment. While preclinical studies have found that microRNAs play an important role in cancer

A big move forward towards defeating glioblastoma

Home-based hypertension program helped 81 percent of participants achieve blood pressure control in seven weeks

Pilot study by Brigham investigators finds that an innovative care-delivery program helped 81 percent of participants achieve blood pressure control in seven weeks Hypertension, or high blood pressure, is a widespread clinical problem affecting nearly half of all adults. Despite the serious consequences that can result from hypertension, which puts patients at increased risk for

Home-based hypertension program helped 81 percent of participants achieve blood pressure control in seven weeks

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Brigham and Women’s Hospital Research

New Information from NCCN on Most Common Type of Cancer; Diagnosed in Millions Every Year
The National Comprehensive Cancer Network (NCCN®) today announced the publication of new NCCN Guidelines for Patients® Basal Cell Skin Cancer (also known as basal cell carcinoma, or BCC), the most ...
Higher fasting ‘hunger hormone’ levels from healthy diet may improve heart health and metabolism
Fasting levels of the “hunger hormone” ghrelin rebound after weight loss and can help reduce belly fat and improve the body’s sensitivity to insulin, according to a study published in the Endocrine ...
A Dallas biotech company and UT Dallas are developing a rapid breath test for COVID-19 screening
A Dallas biotech company and the University of Texas at Dallas are developing a hand-held rapid test to screen for COVID-19 by detecting certain ...
Warning on Tylenol in Pregnancy No Cause for Alarm
One of the painkillers considered safest for women to take during pregnancy -- acetaminophen (Tylenol) -- has recently come under scrutiny for its potential link to adverse fetal outcomes. Earlier ...
New study shows prevalence, treatment outcomes for acute kidney injury from anticancer drugs
To predict acute kidney injury (AKI) as a result of certain anticancer medication, researchers from The Feinstein Institutes for Medical Research, Northwell Health’s Nephrology Division and Department ...

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Brigham and Women’s Hospital Research

Diverse Boston Neighborhoods Recruited For Sweeping Study Of Genetics And Health Outcomes - wgbh.org
September 29, 2021
New analysis shows use and predictors of low-value care in health systems nationwide - EurekAlert
September 27, 2021
Higher fasting ‘hunger hormone’ levels from healthy diet may improve heart health and metabolism - Newswise
October 8, 2021
Warning on Tylenol in Pregnancy No Cause for Alarm - MedPage Today
October 11, 2021
New machine-learning model can identify individuals at risk of rare cardiomyopathy - News-Medical.Net
October 11, 2021

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Brigham and Women’s Hospital Discovery

Global DNA & RNA Banking Services Markets, 2021-2028 - Shifting Focus Towards Personalized Medicine and Genetic Testing
In July 2019, Partners HealthCare, U.S. enrolled more than 100,000 individuals in its precision medicine biobank that supported clinicians and researchers of the Brigham and Women's Hospital ...
Alzheimer's: The heretical and hopeful role of infection
What if dormant microbes trigger the onset of Alzheimer's? It's a theory that could have profound implications for prevention of the disease, writes David Robson.
Mass General Brigham Names Ross D. Zafonte, DO, President of Spaulding Rehabilitation
at Massachusetts General Hospital (MGH) and Chair of PM&R at Brigham and Women’s Hospital (BWH). Zafonte also serves as Earle P. and Ida S. Charlton Professor and Chairman of the Department of ...
Mass General Brigham Names Ross D. Zafonte, DO, President of Spaulding Rehabilitation
at Massachusetts General Hospital (MGH) and Chair of PM&R at Brigham and Women’s Hospital (BWH). Zafonte also serves as Earle P. and Ida S. Charlton Professor and Chairman of the Department of ...
Deb Schrag, MD, MPH, Named Chair of the Department of Medicine at Memorial Sloan Kettering Cancer Center
“My goal is to fertilize a culture that supports innovation and discovery across all types and phases ... From there, Dr. Schrag completed a residency in internal medicine at Brigham and Women’s ...