The Scripps Research Institute (TSRI)

The Scripps Research Institute (TSRI) is a nonprofit American medical research facility that focuses on research and education in the biomedical sciences.

Can fitness trackers and smartwatches predict COVID-19 infection?

A potential new strategy for treating eye diseases that affect millions of people

Asymptomatic Covid-19 infections are a big deal: They are up to 45 percent of SARS-CoV-2 infections

A special molecular switch could be embedded into gene therapies to allow doctors to control dosing

Scientists at Scripps Research in Jupiter have developed a special molecular switch that could be embedded into gene therapies to allow doctors to control dosing. The feat, reported in the scientific journal Nature Biotechnology, offers gene therapy designers what may be the first viable technique for adjusting the activity levels of their therapeutic genes. The lack of

A special molecular switch could be embedded into gene therapies to allow doctors to control dosing

Can these experimental drugs reverse broader aging in humans as they appear to have done in mice?

Salk researchers show how two experimental Alzheimer’s drugs protect the brains of mice from other aspects of aging In mouse models of Alzheimer’s disease, the investigational drug candidates known as CMS121 and J147 improve memory and slow the degeneration of brain cells. Now, Salk researchers have shown how these compounds can also slow aging in

Can these experimental drugs reverse broader aging in humans as they appear to have done in mice?

Remodeling gut microbiomes to fight disease

You are what you eat — right down to the microbiome living in your gut. Diet can affect which microbes are in the intestinal tract, and research has shown that harmful gut microbiome changes can lead to illnesses such as heart disease, obesity and cancer. Today, scientists will report the development of molecules that can

Remodeling gut microbiomes to fight disease

A vaccine for fentanyl addiction?

A vaccine that combines a fentanyl antigen with a tetanus toxoid has been shown to reduce fentanyl choices and increase food choices with effects lasting several months in rats. These results suggest that the vaccine may not only decrease dangerous drug-taking behavior, but can also increase behaviors maintained by healthier non-drug alternatives. The findings are

A vaccine for fentanyl addiction?

A blood test for PTSD?

A cutting-edge blood test discovered by Indiana University School of Medicine researchers could help more accurately diagnose military veterans and other people experiencing post-traumatic stress disorder, and potentially provide more precise treatments and prevention. A study led by psychiatry professor Alexander Niculescu, MD, PhD, and published this week in the high-impact SpringerNature journal Molecular Psychiatry, tracked more than 250 veterans

A blood test for PTSD?

Could an antibiotic protect against neurodegenerative diseases during aging?

The antibiotic minocycline increases the lifespan of aged roundworms and prevents the buildup of proteins, revealing a protective mechanism that could be exploited therapeutically to help prevent neurodegenerative diseases. Now, scientists at Scripps Research have found that minocycline can increase the lifespan of roundworms by preventing the buildup of proteins during aging, according to a

Could an antibiotic protect against neurodegenerative diseases during aging?

Could a vaccine help the opioid epidemic?

Synthetic psychoactive drugs have become a serious public health threat in recent years. This is particularly true of the fentanyls, a large family of synthetic opioids, which can be up to 10,000 times more potent than morphine. Synthetic opioids are highly addictive and, because of their potency, often prove fatal: among the roughly 72,000 drug

Could a vaccine help the opioid epidemic?

How to neutralize the many types of Ebola and other closely related pathogens using rare antibodies

Two new studies by scientists at Scripps Research are bringing Ebola virus’s weaknesses into the spotlight, showing for the first time exactly how human and mouse antibodies can bind to the virus and stop infection—not only for Ebola virus, but for other closely related pathogens as well. The research suggests antibodies like these could be

How to neutralize the many types of Ebola and other closely related pathogens using rare antibodies

An inexpensive urine dipstick test detects the cause of a disease that blinds millions

Scientists at Scripps Research have developed a urine diagnostic to detect the parasitic worms that cause river blindness, also called onchocerciasis, a tropical disease that afflicts 18 to 120 million people worldwide. Described in the journal ACS Infectious Diseases, the new, non-invasive test may provide an inexpensive method of determining in real time whether a person

An inexpensive urine dipstick test detects the cause of a disease that blinds millions

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The Scripps Research Institute (TSRI) Research

David Millar and Rajan Lamicchane, Scripps Research Institute (IMAGE)
on July 31, 2021 at 8:34 pm
The Scripps Research Institute's Professor David Millar (left) and Research Associate Rajan Lamichhane were among the authors of the new paper. Disclaimer: AAAS and EurekAlert! are not responsible ...
Candice Contet and Melissa Herman, The Scripps Research Institute (IMAGE)
on July 31, 2021 at 8:00 am
Scripps Research Institute Assistant Professor Candice Contet (right) and Research Associate Melissa Herman were among the authors of the new paper. Disclaimer: AAAS and EurekAlert! are not ...
The Scripps Research Institute
on June 24, 2021 at 5:00 pm
The Scripps Research Institute (TSRI) is a biomedical research corporation established in La Jolla, California with another site in Jupiter, Florida. Its origins stem from a large endowment from ...
Hiv Aids
on August 17, 2020 at 9:08 pm
In a Major Breakthrough, Researchers Make Cells Resistant to HIV In a path-breaking experiment, scientists at theThe Scripps Research Institute (TSRI) in the United States have discovered a way to ...
San Diego Attractions
on March 15, 2019 at 7:28 pm
Phone 619-234-8291 Sightseeing- Museums Hotels Near San Diego Art Institute/Museum of the Living Artist1439 El Prado (in the House of Charm at Balboa Park, next to the Mingei International Museum ...

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Scripps Research Institute to Pay $10M for Improper Use of NIH Grants - Times of San Diego
September 11, 2020
Scripps Research Institute Forced to Pay $10M For Misusing Funds from NIH Research Grants - Whistleblower News Review
October 7, 2020
The Scripps Research Institute ranked first worldwide in science - The San Diego Union-Tribune
August 10, 2017
Star scientist out at Scripps Research - Science Magazine
August 9, 2019
Scripps Research CEO outlines path to financial sustainability - The San Diego Union-Tribune
February 23, 2018

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The Scripps Research Institute
on June 24, 2021 at 5:00 pm
The Scripps Research Institute (TSRI) is a biomedical research corporation established in La Jolla, California with another site in Jupiter, Florida. Its origins stem from a large endowment from ...
The Scripps Research Institute
on June 24, 2021 at 5:00 pm
The Scripps Research Institute (TSRI) is a biomedical research corporation established in La Jolla, California with another site in Jupiter, Florida. Its origins stem from a large endowment from ...
Chemistry & Physics
on June 21, 2021 at 8:05 pm
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Scientists May Have Found the Chemical Compound That Started Life
on November 6, 2017 at 3:08 pm
But one new discovery, made by chemists at The Scripps Research Institute (TSRI), could help to answer some well-worn questions about how life began on planet Earth: namely, what was the chemical ...