The Scripps Research Institute (TSRI)

The Scripps Research Institute (TSRI) is a nonprofit American medical research facility that focuses on research and education in the biomedical sciences.

A new target for a universal influenza vaccine

Can fitness trackers and smartwatches predict COVID-19 infection?

A potential new strategy for treating eye diseases that affect millions of people

Asymptomatic Covid-19 infections are a big deal: They are up to 45 percent of SARS-CoV-2 infections

A special molecular switch could be embedded into gene therapies to allow doctors to control dosing

Scientists at Scripps Research in Jupiter have developed a special molecular switch that could be embedded into gene therapies to allow doctors to control dosing. The feat, reported in the scientific journal Nature Biotechnology, offers gene therapy designers what may be the first viable technique for adjusting the activity levels of their therapeutic genes. The lack of

A special molecular switch could be embedded into gene therapies to allow doctors to control dosing

Can these experimental drugs reverse broader aging in humans as they appear to have done in mice?

Salk researchers show how two experimental Alzheimer’s drugs protect the brains of mice from other aspects of aging In mouse models of Alzheimer’s disease, the investigational drug candidates known as CMS121 and J147 improve memory and slow the degeneration of brain cells. Now, Salk researchers have shown how these compounds can also slow aging in

Can these experimental drugs reverse broader aging in humans as they appear to have done in mice?

Remodeling gut microbiomes to fight disease

You are what you eat — right down to the microbiome living in your gut. Diet can affect which microbes are in the intestinal tract, and research has shown that harmful gut microbiome changes can lead to illnesses such as heart disease, obesity and cancer. Today, scientists will report the development of molecules that can

Remodeling gut microbiomes to fight disease

A vaccine for fentanyl addiction?

A vaccine that combines a fentanyl antigen with a tetanus toxoid has been shown to reduce fentanyl choices and increase food choices with effects lasting several months in rats. These results suggest that the vaccine may not only decrease dangerous drug-taking behavior, but can also increase behaviors maintained by healthier non-drug alternatives. The findings are

A vaccine for fentanyl addiction?

A blood test for PTSD?

A cutting-edge blood test discovered by Indiana University School of Medicine researchers could help more accurately diagnose military veterans and other people experiencing post-traumatic stress disorder, and potentially provide more precise treatments and prevention. A study led by psychiatry professor Alexander Niculescu, MD, PhD, and published this week in the high-impact SpringerNature journal Molecular Psychiatry, tracked more than 250 veterans

A blood test for PTSD?

Could an antibiotic protect against neurodegenerative diseases during aging?

The antibiotic minocycline increases the lifespan of aged roundworms and prevents the buildup of proteins, revealing a protective mechanism that could be exploited therapeutically to help prevent neurodegenerative diseases. Now, scientists at Scripps Research have found that minocycline can increase the lifespan of roundworms by preventing the buildup of proteins during aging, according to a

Could an antibiotic protect against neurodegenerative diseases during aging?

Could a vaccine help the opioid epidemic?

Synthetic psychoactive drugs have become a serious public health threat in recent years. This is particularly true of the fentanyls, a large family of synthetic opioids, which can be up to 10,000 times more potent than morphine. Synthetic opioids are highly addictive and, because of their potency, often prove fatal: among the roughly 72,000 drug

Could a vaccine help the opioid epidemic?

How to neutralize the many types of Ebola and other closely related pathogens using rare antibodies

Two new studies by scientists at Scripps Research are bringing Ebola virus’s weaknesses into the spotlight, showing for the first time exactly how human and mouse antibodies can bind to the virus and stop infection—not only for Ebola virus, but for other closely related pathogens as well. The research suggests antibodies like these could be

How to neutralize the many types of Ebola and other closely related pathogens using rare antibodies

An inexpensive urine dipstick test detects the cause of a disease that blinds millions

Scientists at Scripps Research have developed a urine diagnostic to detect the parasitic worms that cause river blindness, also called onchocerciasis, a tropical disease that afflicts 18 to 120 million people worldwide. Described in the journal ACS Infectious Diseases, the new, non-invasive test may provide an inexpensive method of determining in real time whether a person

An inexpensive urine dipstick test detects the cause of a disease that blinds millions

A one-two punch of powerful antibodies may be the best way to stop Ebola virus

This landmark study is the first-ever side-by-side comparison of 171 antibodies against Ebola virus. A one-two punch of powerful antibodies may be the best way to stop Ebola virus, reports an international team of scientists in the journal Cell. Their findings suggest new therapies should disable Ebola virus’s infection machinery and spark the patient’s immune system to call

A one-two punch of powerful antibodies may be the best way to stop Ebola virus

A new approach towards the treatment of alcohol use disorder

Activating GPR139 in rats reduced excessive alcohol use and pain of withdrawal Activation of a receptor with no known function in the brain reduces excessive alcohol use and the pain of withdrawal, according to preclinical research in male rats. The study, published in eNeuro, suggests a new approach towards the treatment of alcohol use disorder.

A new approach towards the treatment of alcohol use disorder

RNA-modifying tool can correct genetic diseases

As scientists gain insights into which genes drive diseases, they are pursuing the next logical question: Can gene editing technologies be developed to treat or even cure those diseases? Much of that effort has focused on developing technologies such as CRISPR-Cas9, a protein-based system. At The Scripps Research Institute campus in Florida, chemist Matthew D. Disney,

RNA-modifying tool can correct genetic diseases

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The Scripps Research Institute (TSRI) Research

TSR, Inc. (TSRI) Interactive Stock Chart - Yahoo Finance
As of 03:05PM EDT. Market open. HAUPPAUGE, N.Y., March 02, 2023--TSR, Inc. (Nasdaq: TSRI) ("TSR" or "The Company"), a provider of information technology consulting and recruiting services ...
Immune system drug shows promise in treating alcohol use disorder, a Scripps Research clinical trial reports
Andrews Family. Scripps Research is an independent, nonprofit biomedical institute ranked one of the most influential in the world for its impact on innovation by Nature Index. We are advancing ...
Research Institute Fellows
Since its establishment in 2018, the SLU Research Institute has been dedicated to building an ambitious culture of discovery and innovation at Saint Louis University. Central to our aspiration to ...
FACILITIES AT SCRIPPS
Scripps Oceanography is home to cutting-edge research facilities and scientific equipment ... Pinon Flat Observatory (PFO) is operated by the Institute of Geophysics and Planetary Physics of the ...
The Scripps Research Institute
The Scripps Research Institute (TSRI) is a biomedical research corporation established in La Jolla, California with another site in Jupiter, Florida. Its origins stem from a large endowment from ...

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Immune system drug shows promise in treating alcohol use disorder, a Scripps Research clinical trial reports
Scripps Research is an independent, nonprofit biomedical institute ranked one of the ... medical concerns around the globe. Our drug discovery and development division, Calibr, works hand-in ...
Research Institute Fellows
Since its establishment in 2018, the SLU Research Institute has been dedicated to building an ambitious culture of discovery and innovation at Saint Louis University. Central to our aspiration to ...
Remote Research and Discovery
The AHC is excited to introduce RRAD - Remote Research and Discovery - a new service that enables researchers to access our materials from wherever they are - across the state, across the nation, ...
Research in Focus: Drug Discovery
Five of SLU’s researchers explain their work and the goals of SLU’s Institute ... impactful research garnered attention from the Bill and Melinda Gates Foundation and is now partially funded by the ...
Maker Space
The Maker Space will have multiple goals: Support Scripps graduate and undergraduate teaching, mentoring, and self-guided discovery of new technology ... across UC San Diego by supporting individual ...