Figure 1. Cultivation of the unicellular red alga C. merolae in the laboratory
Scientists find a “switch” to increase starch accumulation in algae
Results from a collaborative study by Tokyo Tech and Tohoku University, Japan, raise prospects for large-scale production of algae-derived starch, a valuable bioresource for biofuels and other renewable materials. Such bio-based products have the potential to replace fossil fuels and contribute to the development of sustainable systems and societies.
A “switch” controlling the level of starch content in algae has been discovered by a research team led by Sousuke Imamura at the Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Tech.
Reported in The Plant Journal, the study focused on the unicellular red alga Cyanidioschyzon merolae pictured in Figure 1. The researchers demonstrated that starch content could be dramatically increased in C. merolae through inactivation of TOR (target of rapamycin), a protein kinase1 known to play an important role in cell growth.
They observed a notable increase in the level of starch 12 hours after inactivation of TOR through exposure to rapamycin, and this led to a remarkable ten-fold increase after 48 hours (see Figure 2).
Figure 2. Algal starch accumulation through TOR inactivation
Compared with the control, inactivation of TOR resulted in an approximately ten-fold increase in starch content in C. merolae after 48 hours.
Importantly, the study details a mechanism underlying this profound increase in starch content. Using a method called liquid chromatography-tandem mass spectrometry (LC-MS/MS), the researchers examined subtle changes in the structure of more than 50 proteins that might be involved in “switching on” the process of starch accumulation. As a result, they pinpointed GLG1 as a key protein of interest. GLG1 acts in a similar way to glycogenin, an enzyme found in yeast and animal cells, which is known to be involved in the initiation of starch (or glycogen) synthesis.
The mechanism, summarized in Figure 3, will be of immense interest to a wide range of industries seeking to scale up biofuel and value-added biochemicals production.
Figure 3. Representation of the “switch” controlling starch accumulation
The phosphorylation status of GLG1, which is regulated by TOR signaling, determines the ON/OFF switch for starch accumulation in the cells. Starch is a good carbon resource for chemicals that are applied in a wide range of industries. (“P” denotes phosphorylation.)
For example, the findings could accelerate the production of environmentally friendly fuel additives, pharmaceuticals, cosmetics, and bioplastics2 that are now in high demand with the phasing out of single-use plastic bags and straws in many parts of the world.
Algae, compared with land plants, are very appealing due to their high photosynthetic productivity and relative ease of cultivation. Starch, triacylglycerols (TAGs) and other algal biomass constituents are increasingly viewed as a promising and powerful way to contribute to the Sustainable Development Goals (SDGs) outlined by the United Nations.
The research team notes that more studies using other algal species, as well as higher plants such as Arabidopsis thaliana, could yield further information about the fundamental molecular mechanisms behind starch accumulation. “This information will help to develop technologies to improve starch biosynthesis productivity and concomitantly improve sustainable biomass and bioenergy production,” Imamura says.
The Latest on: Biofuel
[google_news title=”” keyword=”biofuel” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]
via Google News
The Latest on: Biofuel
- DOE Awards $118 Million to Accelerate Domestic Biofuel Productionon February 3, 2023 at 8:45 am
The U.S. Department of Energy (DOE) announced on January 26, 2023, $118 million in funding for 17 projects to accelerate the production of sustainable biofuels for America’s transporta ...
- Madison company's plant-based biofuel powers engine of Boeing 777 jeton February 3, 2023 at 2:30 am
A Madison company that makes fuel out of plants for cars and airplanes helped power an Emirates test flight Monday to lessen the airline's carbon footprint.
- Global Aviation Biofuel Market 2023 with Upcoming Trends, Growth Rate Analysis by Top Regions, Sales Volume and Industrial Updates Forecast to 2028on February 1, 2023 at 9:03 pm
Feb 02, 2023 (The Expresswire) -- "Final Report will add the analysis of the impact of COVID-19 on this industry." Global “Aviation Biofuel Market” ...
- The next biofuel? MSU researchers focus on switchgrass and ethanol potentialon January 31, 2023 at 7:58 am
The next step in their research is to find the mechanism that slows down photosynthesis within the switchgrass.
- Renewable Hydrocarbon Biofuel Market for the Period 2023 To 2028: With Top Countries Data Analysis and Latest Development Planon January 30, 2023 at 10:16 pm
Global Renewable Hydrocarbon Biofuel Market Report ( 104 Pages) provides exclusive vital statistics, data, information, trends and competitive landscape details in this niche sector. Get a sample PDF ...
- Argus launches world's first biofuel blended ship bunker priceon January 30, 2023 at 9:51 pm
SINGAPORE, Jan. 31, 2023 /PRNewswire/ -- Global energy and commodity price reporting agency Argus today launched the world's first independently assessed price for ship fuel that includes a biofuel ...
- Raft: A Guide to Biofuel and Pipeson January 28, 2023 at 9:26 am
Biofuel is required for some advanced machinery, but making it takes some doing and piping it is surprisingly tricky. A player who discovers every secret on Balboa Island in Raft will get access ...
- Biden administration awards $118 million for biofuel projectson January 27, 2023 at 9:46 am
The Department of Energy on Thursday announced a grant of $118 million in funding for domestic production of biofuels, part of the Biden administration’s emission-reduction goals. Funding was divided ...
- Discovery advances biofuel crop that could curb dependence on fossil fuelon January 26, 2023 at 4:01 pm
Researchers have solved a puzzle that could help switchgrass realize its full potential as a low-cost, sustainable biofuel crop and curb our dependence on fossil fuels.
via Bing News
