There just aren’t enough kidney transplants available for the millions of people with renal failure.
Aside from a transplant, the only alternative for patients is to undergo regular dialysis sessions to clear harmful cellular waste from their bodies. Now, scientists report in ACS Nanoa new urea sorbent that could accelerate progress toward the development of a lightweight, wearable artificial kidney with the potential to make dialysis more convenient, comfortable and effective.
Dialysis typically requires three visits every week to a health care center, where patients are tethered to a machine for hours. Not only is this cumbersome, but health outcomes with the treatment are poor. The problem is that kidneys filter blood around the clock; dialysis just can’t do as good of a job when performed for only a few times each week. Scientists are eager to develop an artificial kidney that could be worn all the time, continuously performing dialysis. One obstacle, though, is urea, which must be removed to maintain the body’s nitrogen balance. Currently, dialysis deals with urea using an enzyme that breaks the molecule down into ammonia and carbon dioxide, but the amount of material required to perform this reaction is too big and heavy to be comfortably worn on the body. So, Babak Anasori, Yury Gogotsi and colleagues wanted to try a new approach.
The researchers turned to an emerging nanomaterial called MXene, two-dimensional nanosheets of metal carbides. Instead of breaking down urea, MXene can capture the compound by sandwiching urea molecules between its nanometer-thin layers. At room temperature, the material could capture 94 percent of urea from the discarded materials from dialysis machines. When tested at body temperature (98.6 F), the material could hold onto even more urea. Furthermore, MXene did not kill cells, suggesting that it could be safely used in people. The researchers conclude that the material could help turn the concept of a comfortably wearable artificial kidney into a reality.
Learn more: Taking steps toward a wearable artificial kidney
The Latest on: Wearable artificial kidney
via Google News
The Latest on: Wearable artificial kidney
- A Wearable Artificial Kidney: Dream or Reality?on December 1, 2021 at 4:00 pm
[5,6,7] Although the idea of a wearable artificial kidney (WAK) is not new, it is only the advent of nanotechnology and miniaturization that has made the vital qualities of efficiency and safety ...
- Kidney Stone Extraction Balloons Industry Survey Report on 2021 Market Opportunities and Threatson November 30, 2021 at 8:42 am
The "Kidney Stone Retrieval Device Market Analysis to 2028" is a specialized and in-depth study of the biotechnology industry with a special focus on the global market trend analysis. The report ...
- Kidney Cancer Drugs Market 2021 Share, Trends, Overview, Growth Trajectory, Industry Future Scope And Latest Advancementson November 29, 2021 at 7:48 pm
Get up to 33% off on ALL market research reports at The Business Research Company's holiday sale; buy now! https://www.thebusinessresearchcompany.com/global-market ...
- Willem Kolff’s Artificial Organson November 29, 2021 at 3:59 pm
The hospital there was glad for the help and paid the young internist enough to start working on his kidney treatments again. This time, he would concentrate on an artificial kidney. Dr. Kolff had ...
- Dialysis Equipment Market is expected to expand at a CAGR of 4.8% over the forecast period (2018–2028)on November 25, 2021 at 3:03 am
In a new development, the Kidney Research Institute of the University of Washington is currently developing a wearable artificial kidney that is expected to go into clinical trials in 2022. This could ...
- Behind the Invention: Wearable Artificial Kidneyon November 18, 2021 at 4:00 pm
First of all, there is a pill burden. "My patients need to eat 20 to 30 pills a day," Victor Gura, MD, an internist, nephrologist, and inventor of the Wearable Artificial Kidney (WAK) told MD&M West ...
- Portable in-home hemodialysis device may be in clinical trials by 2017on November 16, 2021 at 4:00 pm
Not surprisingly, the development of an artificial kidney has been the subject of feverish activity over the last few years, and in February 2014, FDA approved the start of the first human clinical ...
- Dialysis Equipment Market is expected to expand at a CAGR of 4.8% over the forecast period (2018–2028) | Regional Outlook, Share, Challengeson November 16, 2021 at 3:13 am
In a new development, the Kidney Research Institute of the University of Washington is currently developing a wearable artificial kidney that is expected to go into clinical trials in 2022.
- Kidney Patients Mobilize For Greater Disease Research And Innovationon November 11, 2021 at 1:38 am
The Decade of the Kidney™ Includes New Therapies, Home Dialysis, and Artificial Organs WASHINGTON, Nov. 8, 2021 /PRNewswire/ -- The American Association of Kidney Patients (AAKP), the largest ...
via Bing News