According to the National Institute of Mental Health (NIMH), 4.4 percent of the population of the United States will have bipolar disorder at one point in their lives.
While the precise causes of such, often debilitating, psychiatric conditions remain unknown, scientists do know that both genes and the environment play a role.
New research that now appears in the journal Frontiers in Microbiology highlights the fact that environmental factors such as viruses may be the driving force behind these disorders.
An international team of scientists led by Bhupesh Prusty — from the Department of Microbiology at the University of Würzburg in Germany — discovered that in the brains of people who lived with bipolar and major depression, a class of neurons called Purkinje cells was infected with the herpesvirus HHV-6A.
Purkinje neurons are inhibitory brain cells located in the human cerebellum, which is the brain area responsible for controlling movement, muscles, balance, and posture.
However, some research has also tied this brain region to language, cognition, and mood.
How HHV-6 may cause depression, bipolar
Prusty and team started from the hypothesis that the human herpesviruses HHV-6A and HHV-6B may drive the development of psychiatric disorders.
So, they examined two large cohorts of brain biopsies from the Stanley Medical Research Institute in Kensington, MD.
“We were able to find active infection of HHV-6 predominantly within Purkinje cells of human cerebellum in bipolar and major depressive disorder patients,” Prusty reports.
The Latest on: Herpesvirus HHV-6A
via Google News
The Latest on: Herpesvirus HHV-6A
- Why the herpes virus awakenson May 17, 2022 at 4:19 am
Researchers have now discovered how the virus reactivates after lying dormant in the body. The findings could be important for long COVID research.Chickenpox is a vivid example. The cause of the itchy ...
- Herpesvirus infection may increase the risk of developing diabeteson May 12, 2022 at 8:05 pm
Herpesviruses are one of the most prevalent viruses in humans, with eight types currently known: herpes simplex viruses (HSV) 1 and 2, varicella-zoster virus (VZV), Epstein-Barr virus (EBV), ...
- Newly discovered link between diabetes risk and herpesvirus infectionon May 12, 2022 at 7:53 pm
Two common herpesviruses have been associated with the onset of prediabetes in a new study led by researchers in Germany. The findings build on a growing body of evidence connecting viral infections ...
- Discovery of cell protein that keeps Kaposi's sarcoma herpesvirus dormanton May 11, 2022 at 10:37 am
A team of UC Davis researchers has identified a protein in the cancer cell's nucleus as a critical agent keeping Kaposi's sarcoma-associated herpesvirus (KSHV) dormant and undetected by the body's ...
- The Secret to Herpesvirus Awakeningon May 5, 2022 at 1:22 am
Dormant herpesviruses induce their reactivation via a previously unknown cellular mechanism mediated by a viral microRNA, a new study has shown.
- How Herpes Viruses Trigger Their Own Awakeningon May 4, 2022 at 9:17 am
The virus probably only causes problems when it wakes up repeatedly. Human herpesvirus 6 (HHV-6) is the common collective name for human betaherpesvirus 6A (HHV-6A) and human betaherpesvirus 6B ...
- Human Herpesvirus-6 Entry into Host Cellson May 1, 2022 at 5:01 pm
Human herpesvirus-6 (HHV-6) belongs to the herpesvirus family and is categorized into variant A and B (HHV-6A and HHV-6B). Primary HHV-6 infection in children and its related diseases are almost ...
- Human Herpesvirus-6 Entry into Host Cellson April 5, 2022 at 5:00 pm
Human herpesvirus (HHV) -6 is a T-cell tropic virus ... HHV-6 can be classified into two variants, HHV-6 variant A (HHV-6A) and variant B (HHV-6B) based on their genetic, antigenic and growth ...
via Bing News