A cell visualized with the PRISM method
via T. Lasser/EPFL
Super resolution microscopy is a technique that can see beyond the diffraction of light and provides unprecedented views of cells and their interior structures and organelles.
An EPFL team has developed a technique that can perform both 3D super resolution microscopy and fast 3D phase imaging in a single instrument.
This unique 4D microscope combines a sensitivity and high time resolution of phase imaging with the specifically and high spatial resolution of fluorescence microscopy. This allows the direct visualization and Analysis of subcellular structures in living cells without labeling.
These technical advances enable high-resolution visualization of the formation of pathological alpha-synuclein aggregates in hippocampal neurons. It is hoped that it will become a regular workhorse for neuroscience and biology.
Learn more: Super-resolution microscopy in both space and time
The Latest on: Super resolution microscopy
via Google News
The Latest on: Super resolution microscopy
- Ludwig-Maximilians-Universität München: Fluorescence microscopy at highest spatial and temporal resolutionon January 16, 2021 at 11:28 am
Only a few years ago, an ostensibly fundamental resolution limit in optical microscopy was superseded – a breakthrough which in 2014 led to the Nobel Prize in Chemistry for super-resolution ...
- Fluorescence microscopy at highest spatial and temporal resolutionon January 15, 2021 at 7:20 am
(Nanowerk News) Only a few years ago, an ostensibly fundamental resolution limit in optical microscopy was superseded - a breakthrough which in 2014 led to the Nobel Prize in Chemistry for ...
- Fluorescence microscopy at highest spatial and temporal resolutionon January 15, 2021 at 6:06 am
LMU researchers simplify the MINFLUX microscope and have succeeded in differentiating molecules that are extremely close together and tracking their dynamics.
- ZEISS announces collaborative research partnership with Max Planck Florida Institute for Neuroscienceon January 15, 2021 at 2:52 am
LSM 980 NLO confocal microscope with GRIN lenses in combination with Airyscan ... provides a unique combination of gentle super-resolution imaging and high sensitivity. Combining Airyscan with GRIN ...
- Avalanching nanoparticles may advance real-time bioimaging of cell's organelles and proteinson January 14, 2021 at 6:54 am
Since the earliest microscopes, scientists have been on a quest to build instruments with finer and finer resolution to image a cell's proteins - the tiny machines that keep cells, and us, running.
- Avalanching nanoparticles break barriers to imaging cells in real timeon January 13, 2021 at 9:13 am
Study could lead to simple, high-resolution bioimaging in real time by overcoming a fundamental property of light.
- Shine on: Avalanching nanoparticles break barriers to imaging cells in real timeon January 13, 2021 at 8:03 am
Since the earliest microscopes, scientists have been on a quest to build instruments with finer and finer resolution to image a cell's proteins—the tiny machines that keep cells, and us, running. But ...
- First Nanomaterial Developed That Demonstrates “Photon Avalanching” – Extreme Nonlinear Optical Behavior and Efficiencyon January 13, 2021 at 8:02 am
Researchers develop the first nanomaterial that demonstrates "photon avalanching;" finding could lead to new applications in sensing, imaging, and light detection. Researchers at Columbia Engineering ...
- Superresolution microscope resolves features down to 137 nmon January 12, 2021 at 6:33 am
The OptoNano 200 superresolution microscope system incorporates optical microsphere nanoscopy (OMN) technology to resolve features down to 137 nm in ambient environments without the need to condition ...
- New Method for Fluorescence Microscopy Developedon January 3, 2021 at 7:16 am
New Technique to Achieve Super-resolution Microscopy Developed Scientists have developed an advanced imaging technique to achieve super-resolution microscopy at unprecedented speeds.
via Bing News
