A cell visualized with the PRISM method
via T. Lasser/EPFL
Super resolution microscopy is a technique that can see beyond the diffraction of light and provides unprecedented views of cells and their interior structures and organelles.
An EPFL team has developed a technique that can perform both 3D super resolution microscopy and fast 3D phase imaging in a single instrument.
This unique 4D microscope combines a sensitivity and high time resolution of phase imaging with the specifically and high spatial resolution of fluorescence microscopy. This allows the direct visualization and Analysis of subcellular structures in living cells without labeling.
These technical advances enable high-resolution visualization of the formation of pathological alpha-synuclein aggregates in hippocampal neurons. It is hoped that it will become a regular workhorse for neuroscience and biology.
Learn more: Super-resolution microscopy in both space and time
The Latest on: Super resolution microscopy
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The Latest on: Super resolution microscopy
- Microscopy technique enables 3D super-resolution nanometer-scale imagingon June 27, 2022 at 8:07 am
Over the last two decades, microscopy has seen unprecedented advances in speed and resolution. However, cellular structures are essentially three-dimensional, and conventional super-resolution ...
- Microscopy technique enables 3D super-resolution nanometer-scale imagingon June 24, 2022 at 1:53 pm
Microscopy technique enables 3D super-resolution nanometer-scale imaging Date: June 24, 2022 Source: University of Göttingen Summary: Over the last two decades, microscopy has seen unprecedented ...
- Microscopy technique enables 3D super-resolution nanometre-scale imagingon June 24, 2022 at 12:20 pm
Over the last two decades, microscopy has seen unprecedented advances in speed and resolution. However, cellular structures are essentially three-dimensional, and conventional super-resolution ...
- Super-Resolution Imaging Method For Multiple Fluorescence Microscopy Applicationson June 23, 2022 at 10:01 am
The excited fluorophore's de-excitation rate with optical modulation is an important tool to achieve super-resolution in microscopy techniques, including ground state depletion microscopy, stimulated ...
- TU Delft: Track-and-trace method predicts best possible resolution in microscopyon June 21, 2022 at 9:19 pm
TU Delft scientists provide insight into the limitations of super-resolution microscopy and offer a new calculation method to determine maximum resolution. The major precision improvements previously ...
- Track-and-trace method predicts best possible resolution in microscopyon June 21, 2022 at 5:00 pm
Super-resolution microscopy is a groundbreaking technology that allows researchers to look inside living cells. The technique uses luminescent proteins that can be found in jellyfish, for example.
- Global Super-Resolution Microscope Market 2022 Upcoming Trends, Regional Study, Top Manufacturers Profiles, SWOT Analysis and Forecast by 2028on June 19, 2022 at 2:22 pm
Jun 19, 2022 (CDN Newswire via Comtex) -- The Global Super-Resolution Microscope Market report by MarketandResearch.biz studies the market for the forecast period of 2022-2028 and presents an in ...
- Super-Resolution Microscopes Market 2022 Growth Analysis By Size, Share, News, Demand, Opportunity 2030on June 14, 2022 at 4:07 am
Super-resolution microscopy is a technique used to observe biological structures at a higher resolution than a conventional light microscopy. It is widely used in different sectors such as ...
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