SMARTPHONE-CONTROLLED DESIGN PRECISELY DELIVERS MEDICATION
Researchers from the University of Nebraska-Lincoln, Harvard Medical School and MIT have designed a smart bandage that could eventually heal chronic wounds or battlefield injuries with every fiber of its being.
The bandage consists of electrically conductive fibers coated in a gel that can be individually loaded with infection-fighting antibiotics, tissue-regenerating growth factors, painkillers or other medications.
A microcontroller no larger than a postage stamp, which could be triggered by a smartphone or other wireless device, sends small amounts of voltage through a chosen fiber. That voltage heats the fiber and its hydrogel, releasing whatever cargo it contains.
“This is the first bandage that is capable of dose-dependent drug release,” Tamayol said. “You can release multiple drugs with different release profiles. That’s a big advantage in comparison with other systems. What we did here was come up with a strategy for building a bandage from the bottom up.
“This is a platform that can be applied to many different areas of biomedical engineering and medicine.”
The team envisions its smart bandage being used initially to treat chronic skin wounds that stem from diabetes. More than 25 million Americans – and more than 25 percent of U.S. adults 65 and older – could suffer from such wounds. The Centers for Disease Control and Prevention has estimated that diabetes cases will double or triple by the year 2050.
“The medical cost associated with these types of wounds is tremendous,” Tamayol said. “So there is a big need to find solutions for that.”
Those wounded in combat might also benefit from the bandage’s versatility and customizability, Tamayol said, whether to stimulate faster healing of bullet and shrapnel wounds or prevent the onset of infection in remote environments.
“Soldiers on the battlefield may be suffering from a number of different injuries or infections,” he said. “They might be dealing with a number of different pathogens. Imagine that you have a variable patch that has antidotes or drugs targeted toward specific hazards in the environment.”
Existing bandages range from basic dry patches to more advanced designs that can passively release an embedded medication over time. To evaluate the potential advantages of their smart bandage, Tamayol and his colleagues at Harvard ran a series of experiments.
In one, the researchers applied a smart bandage loaded with growth factor to wounded mice. When compared with a dry bandage, the team’s version regrew three times as much of the blood-rich tissue critical to the healing process.
Another experiment showed that an antibiotic-loaded version of the bandage could eradicate infection-causing bacteria. Collectively, Tamayol said, the experiments also demonstrated that the heat needed to release the medications did not affect their potency.
Though the researchers have patented their design, it will need to undergo further animal and then human testing before going to market. That could take several years, though the fact that most of the design’s components are already approved by the Food and Drug Administration should streamline the process, Tamayol said.
In the meantime, he said, the researchers are also working to incorporate thread-based sensors that can measure glucose, pH and other health-related indicators of skin tissue. Integrating that capability would allow the team to create a bandage that could autonomously deliver proper treatments.
Learn more: Smart bandage could promote better, faster healing
The Latest on: Smart bandage
[google_news title=”” keyword=”smart bandage” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]
- Cheap ‘smart’ bandage heals infected, chronic wounds — faston March 24, 2023 at 3:41 pm
We’re truly on the cutting edge of medicine, now. A “smart” bandage is on the horizon, as researchers develop a product that can monitor healing and provide antibiotics to the injury site, as well as ...
- This Smart Bandage Zaps Your Wounds to Heal Them Fasteron March 24, 2023 at 2:00 pm
That’s why researchers at Caltech developed a new smart bandage that can help speed up the healing process for those susceptible to chronic wounds. In a study published Friday in the journal Science ...
- ‘Smart bandage’ with biosensors could help chronic wounds heal, study claimson March 24, 2023 at 1:08 pm
Scientists test device that can monitor and stimulate burns, diabetic ulcers and non-healing surgical wounds A smart bandage that can monitor chronic wounds and help them to heal has been developed by ...
- Electronic wound dressing releases drugs to help injuries healon March 24, 2023 at 11:01 am
A stretchy bandage that can monitor wounds, release drugs as needed and perform electrical stimulation has been shown to accelerate healing in rodents. Wei Gao at the California Institute of ...
- 'Smart' bandages monitor wounds and provide targeted treatmenton March 24, 2023 at 11:01 am
A new kind of smart bandage developed at Caltech may make treatment of these wounds easier, more effective and less expensive. These smart bandages were developed in the lab of Wei Gao, assistant ...
- Smart bandages can monitor wounds, aid healing, researchers sayon March 24, 2023 at 11:00 am
Development of a "smart bandage" not only can deliver medication to wounds, but also monitor the progress of healing and even create off a low-level electrical field to promote tissue repair, ...
- New ‘smart’ bandage can monitor and treat woundson March 24, 2023 at 9:24 am
Researchers at the California Institute of Technology - or Caltech - have engineered the clever, stretchy bandage which will revolutionize wound treatment. Though not currently available to buy, ...
- Smart Bandage Market Share and Forecast till 2028on March 21, 2023 at 5:50 am
Mar 21, 2023 (The Expresswire) -- The "Smart Bandage Market" Study Describes how the technology industry is evolving and how major and emerging players in the industry are responding to long term ...
- Smart Bandage Market Statistics and Industry Share Analysis Forecast 2023-2028on March 16, 2023 at 12:22 am
The “Smart Bandage Market” Report provides accurate information on industry SWOT analysis, CAGR status, product ...
- Smart Bandage Market Size & Revenue by 2028:...on March 15, 2023 at 5:12 am
Pune, March 15, 2023 (GLOBE NEWSWIRE) -- Xcellent Insights announces the release of the recent report "Smart Bandage Market Size & Revenue by 2028: A Comprehensive Analysis of Global Industry ...
via Google News and Bing News