Researchers at Case Western Reserve University School of Medicine have developed a method that could make magnetic resonance imaging—MRI—multicolor.
Current MRI techniques rely on a single contrast agent injected into a patient’s veins to vivify images. The new method uses two at once, which could allow doctors to map multiple characteristics of a patient’s internal organs in a single MRI. The strategy could serve as a research tool and even aid disease diagnosis.
“The method we developed enables, for the first time, the simultaneous detection of two different MRI contrast agents,” said Chris Flask, PhD, Associate Professor of Radiology, Biomedical Engineering, and Pediatrics, and Director of the Imaging Resource Core at Case Western Reserve University School of Medicine. Two contrast agents could include one specifically targeting diseased tissue, and one designed to show healthy tissue, for example. The new method would enable immediate comparisons of how each agent distributes in the same patient.
“This multi-agent detection capability has the potential to transform molecular imaging, as it provides a critical translational pathway for studies in patients,” said Flask. It also provides a unique imaging platform to rigorously study molecular therapies.” Therapies could include those targeting biomarkers or other detectable molecules associated with diseases.
Flask and colleagues recently described their new method in Nature Scientific Reports. The paper describes how two contrast agents, gadolinium and manganese, can be detected and independently quantified during MRIs. The authors span 11 departments at Case Western Reserve, uniting engineers, nurses, clinicians, and basic science researchers. They also include several members of the Case Comprehensive Cancer Center. According to the authors, their results provide “an adaptable, quantitative imaging framework to assess two MRI contrast agents simultaneously for a wide variety of imaging applications.”
The researchers have begun to investigate widespread practical applications for the new MRI approach. Said Flask, “In this initial paper, we validated our new methodology, opening the possibility for numerous follow-on application studies in cancer, genetic diseases such as cystic fibrosis, and metabolic diseases such as diabetes.”
Learn more: Multicolor MRIs Could Aid Disease Detection
The Latest on: Multicolor MRIs
[google_news title=”” keyword=”multicolor MRIs” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]
- MagCorp, Philips partner to bring power of MagLab research to MRI techon November 30, 2022 at 10:20 am
The partnership creates a direct path for researchers to develop a report on the future landscape for MRI magnets.
- Machine learning is helping us understand Alzheimer’s diseaseon November 29, 2022 at 4:52 am
Using machine learning to pinpoint the most accurate means and timelines for anticipating the advancement of Alzheimer’s disease ...
- MRI Guided Neurosurgical Ablation Market to grow at a rate of 5% by 2028 | Get Customized Reportson November 29, 2022 at 4:36 am
The global MRI Guided Neurosurgical Ablation Market was at US$ 154 Mn in 2021, and is projected to reach US$ 216.3 Mn by 2028, rising at a CAGR of 5% from 2022 to 2028. MRI-guided neurosurgical ...
- Dimethyl fumarate halts radiologic progression of multiple sclerosis: Studyon November 29, 2022 at 2:22 am
A new study published in Annals of Neurology suggests that the advantage of a disease-modifying treatment in radiologically isolated syndrome (RIS) patients in averting a first acute ...
- Machine learning pinpoints the most accurate timelines for predicting Alzheimer's progressionon November 28, 2022 at 3:24 pm
A Cornell-led collaboration used machine learning to pinpoint the most accurate means, and timelines, for anticipating the advancement of Alzheimer's disease in people who are either cognitively ...
- Machine learning gives nuanced view of Alzheimer’s stageson November 28, 2022 at 9:42 am
A Cornell-led collaboration used machine learning to pinpoint the most accurate means, and timelines, for anticipating the advancement of Alzheimer’s disease in people who are either cognitively ...
- HeartVista to Expand Beyond Heart MRIs, Changes Name to Vista.ai to Reflect Wider Focuson November 27, 2022 at 8:10 am
Company extending its One Click MRI™ acquisition software to other anatomies to make MRIs faster, easier and accessible to all Company extending One Click MRI acquisition software to other ...
- HeartVista to Expand Beyond Heart MRIs, Changes Name to Vista.ai to Reflect Wider Focuson November 27, 2022 at 7:31 am
Company extending its One Click MRI™ acquisition software to other anatomies to make MRIs faster, easier and accessible to all CHICAGO, Nov. 27, 2022 /PRNewswire/ -- HeartVista, a pioneer and ...
- Medicare won't fund MRIs for patients with new MRI-safe pacemakerson November 26, 2022 at 7:58 pm
Hospitals across the country have been cranking out news releases this week about patients who are among the first to receive a new MRI-safe pacemaker from Medtronic. But Medicare patients with ...
- MRI Scans Show Covid Does Impact Your Brain, Say Expertson November 22, 2022 at 7:00 am
The brains of 46 people who caught Covid within the last six months were analysed by scientists using MRI scans ... “Covid-19 has multi-dimensional effects on the body,” Prof.
via Google News and Bing News