Researchers at Case Western Reserve University School of Medicine have developed a method that could make magnetic resonance imaging—MRI—multicolor.
Current MRI techniques rely on a single contrast agent injected into a patient’s veins to vivify images. The new method uses two at once, which could allow doctors to map multiple characteristics of a patient’s internal organs in a single MRI. The strategy could serve as a research tool and even aid disease diagnosis.
“The method we developed enables, for the first time, the simultaneous detection of two different MRI contrast agents,” said Chris Flask, PhD, Associate Professor of Radiology, Biomedical Engineering, and Pediatrics, and Director of the Imaging Resource Core at Case Western Reserve University School of Medicine. Two contrast agents could include one specifically targeting diseased tissue, and one designed to show healthy tissue, for example. The new method would enable immediate comparisons of how each agent distributes in the same patient.
“This multi-agent detection capability has the potential to transform molecular imaging, as it provides a critical translational pathway for studies in patients,” said Flask. It also provides a unique imaging platform to rigorously study molecular therapies.” Therapies could include those targeting biomarkers or other detectable molecules associated with diseases.
Flask and colleagues recently described their new method in Nature Scientific Reports. The paper describes how two contrast agents, gadolinium and manganese, can be detected and independently quantified during MRIs. The authors span 11 departments at Case Western Reserve, uniting engineers, nurses, clinicians, and basic science researchers. They also include several members of the Case Comprehensive Cancer Center. According to the authors, their results provide “an adaptable, quantitative imaging framework to assess two MRI contrast agents simultaneously for a wide variety of imaging applications.”
The researchers have begun to investigate widespread practical applications for the new MRI approach. Said Flask, “In this initial paper, we validated our new methodology, opening the possibility for numerous follow-on application studies in cancer, genetic diseases such as cystic fibrosis, and metabolic diseases such as diabetes.”
Learn more: Multicolor MRIs Could Aid Disease Detection
The Latest on: Multicolor MRIs
[google_news title=”” keyword=”multicolor MRIs” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]
- AI may aid in diagnosing adolescents with ADHDon November 29, 2023 at 2:00 am
Using artificial intelligence (AI) to analyze specialized brain MRI scans of adolescents with and without attention-deficit/hyperactivity disorder (ADHD), researchers have found significant ...
- Philips showcases helium-free mobile MRI at RSNAon November 26, 2023 at 11:18 pm
BlueSeal MR Mobile’s magnet technology advances patient outcomes and access to care with high quality diagnostic imaging and enhanced workflows.
- Philips Unveils World's First Mobile MRI System With Helium-free Operationson November 26, 2023 at 6:45 pm
Royal Philips (PHG) has unveiled the world's first mobile MRI system with helium-free operations. Unlike other mobile MRI scanners, ...
- Philips showcases world’s first mobile MRI system with helium-free operations at #RSNA23on November 26, 2023 at 7:00 am
Philips Mobile MRI system expanding access to care Interior view of Philips Mobile MR Philips MR Mobile connected to Philips’ Radiology Operations Command Center (ROCC) November 26, 2023 BlueSeal MR ...
- Canada’s most powerful MRI system arrives at Westernon November 23, 2023 at 10:22 am
CFMM, located at Robarts Research Institute, houses Canada’s most advanced ultra-high field MRI platform, including Siemens 3T and 7T human MRI scanners and a Bruker 9.4T pre-clinical scanner.
- AI may diagnose autism in children much earlier, study sayson November 21, 2023 at 2:00 am
A novel artificial intelligence system could diagnose autism much earlier in children, according to research to be presented this week at the annual meeting of the Radiological Society of North ...
- Fascinating MRIs reveal what it looks like in the brain when watching your sports team lose AND winon November 21, 2023 at 2:00 am
These men watched a compilation of matches while their brains were scanned by magnetic resonance imaging (MRI). Specifically, the collections included videos of the teams scoring on their rivals ...
- Will undergo MRI on ankleon November 20, 2023 at 1:10 pm
Both will need MRIs. Dean has dealt with shoulder, neck and concussion issues in 2023 but has missed just one game. The Bucs travel to Indy to face the Colts in Week 12.
- Safely Shifting MRIs for Seizure Evaluation to the Outpatient Setting.on November 19, 2023 at 4:00 pm
When a patient is admitted for seizure-like activity, in addition to obtaining a thorough history and physical exam, the evaluation may include a neurology consultation, EEG, and brain MRI. The cost ...
- MRIs cancelled as car blocks mobile unit space at Louth Hospitalon November 17, 2023 at 4:05 am
Patients trying to attend their appointment in the mobile MRI scanner at Louth County Hospital turned up at the hospital to find their appointment had been cancelled as the mobile unit could not ...
via Google News and Bing News