
via American Chemical Society
Fast, accurate and inexpensive medical tests in a doctor’s office are only possible for some conditions. To create new in-office diagnostics for additional diseases, researchers report in the journal ACS Nano a new technique that uses ultrasound to concentrate fluorescently labeled disease biomarkers otherwise impossible to detect with current equipment in an office setting.
The markers’ signal could someday be analyzed via a smartphone app.
Ultrasound is a safe, noninvasive, inexpensive and portable technique best known for monitoring pregnancies. But these high-frequency acoustic waves can also be used to gently handle blood components, cells and protein crystals at the microscopic level. With an eye toward point-of-care diagnostic applications, Tony Huang, Zhangming Mao and colleagues wanted to harness these sound waves to help detect even smaller particles and biomarkers for diseases such as cancer that often require special laboratory equipment to detect.
The researchers developed an acoustofluidic chip that, though vibrations, can form a streaming vortex inside a tiny glass capillary tube using a minimal amount of energy. Testing showed that the vortex could force nanoparticles ranging in diameter from 80 to 500 nanometers to swirl into the center of the capillary. The nanoparticles captured biomarkers labeled with a fluorescent tag, concentrating them in the capillary to boost their signal. This increased brightness could make the signal readable with a smartphone camera.
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The Latest on: Point-of-care disease diagnostics
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via Google News
The Latest on: Point-of-care disease diagnostics
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[36] Most infectious disease POC assays are configured ... was utilized in the production of this manuscript. Point-of-care (POC) diagnostic test requirements and usage may be very different ...
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Ad Astra’s QScout rapid result haematology analyser can provide WBC counts, neutrophil-to-lymphocyte ratio, and immature granulocytes report.
- Advancing Rapid Point-of-care Viral Diagnostics to a Clinical Settingon November 15, 2023 at 4:00 pm
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Wilmington, Delaware, Oct. 27, 2023 (GLOBE NEWSWIRE) -- Allied Market Research recently published a report, titled, "Point of Care Diagnostics Market by Product (Cholesterol Test Strips, Glucose ...
- CRISPR-Based Point-of-Care Diagnostics of SARS-CoV-2on October 24, 2023 at 3:00 am
The recent outbreak of the Coronavirus Disease 2019 (COVID-19 ... rapid, affordable, mobile, point of care molecular diagnostics. Learning Objectives: 1. Discuss current challenges in developing ...
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- Point-of-Care Diagnostics for Veterinary Useon July 17, 2022 at 12:57 pm
As the world population continues to grow, great pressure is placed on agriculture to provide an adequate supply of food. This requires not only an increase in food production but also in food safety.
via Bing News