Participants using a game-based app report benefits
Researchers have found promising results for treating depression with a video game interface that targets underlying cognitive issues associated with depression rather than just managing the symptoms.
“We found that moderately depressed people do better with apps like this because they address or treat correlates of depression,” said Patricia Areán, a UW Medicine researcher in psychiatry and behavioral sciences.
The first study enrolled older adults diagnosed with late-life depression into a treatment trial where they were randomized to receive either a mobile, tablet-based treatment technology developed by Akili Interactive Labs called Project: EVO or an in-person therapy technique known as problem-solving therapy (PST).
Project: EVO runs on phones and tablets and is designed to improve focus and attention at a basic neurological level. The results, published Jan. 3 in the journal Depression and Anxiety, showed that the group using Project: EVO demonstrated specific cognitive benefits (such as attention) compared to the behavioral therapy, and saw similar improvements in mood and self-reported function. Joaquin A. Anguera, a University of California, San Francisco (UCSF), researcher in neurology and psychiatry, is the lead author, and Areán is the senior author. The researchers have no commercial interests in the intervention manufactured by Akili Interactive Labs in Boston. The studies were funded by the National Institute of Mental Health.
“While EVO was not directly designed to treat depressive symptoms; we hypothesized that there may indeed be beneficial effects on these symptoms by improving cognitive issues with targeted treatment, and so far, the results are promising,” said Anguera.
People with late-life depression (60+) are known to have trouble focusing their attention on personal goals and report trouble concentrating because they are so distracted by their worries. Akili’s technology was designed to help people better focus their attention and to prevent people from being easily distracted.
Arean said most of the participants had never used a tablet, let alone played a video game, but compliance was more than 100 percent. The participants were required to play the game five times a week for 20 minutes, but many played it more. Participants in this arm of the study also attended weekly meetings with a clinician. The meetings served as a control for the fact that participants in the problem-solving therapy arm were seen in person on a weekly basis, and social contact of this nature can have a positive effect on mood.
A second study, which was another joint effort by UW and UCSF, randomized more than 600 people across the United States assessed as moderately or mildly depressed to one of three interventions: Akili’s Project: EVO; iPST, an app deployment of problem-solving therapy; or a placebo control (an app called Health Tips, which offered healthy suggestions).
Areán, the lead researcher on the study published Dec. 20 in the Journal of Medical Internet Research (JIMR), found that people who were mildly depressed were able to see improvements in all three groups, including the placebo. However, those individuals who were more than mildly depressed showed a greater improvement of their symptoms following their use of Project EVO or iPST versus the placebo.
Areán said much of her research is aimed at providing effective treatment to people who need it, and these results provide great potential for helping people who don’t have the resources to access effective problem solving therapy. But, she stressed, the apps should be used under clinical supervision because without a human interface, people were not as motivated to use it. In the JIMR study, 58 percent of participants did not download the app.
Akili’s technologies are based on a proprietary neuroscience approach developed to target specific neurological systems through sensory and digital mechanics. The company’s technology platform used in this trial is based on cognitive science exclusively licensed from the lab of Dr. Adam Gazzaley at UCSF, and adaptive algorithms developed at Akili, which are built into action video game interfaces. The technology targets an individual’s core neurological ability to process multiple streams of information.
Project: EVO is undergoing multiple clinical trials for use in cognitive disorders — including Alzheimer’s disease, traumatic brain injury and pediatric attention deficit hyperactivity disorder (ADHD), and the company is on path for potential FDA clearance to treat pediatric ADHD.
[osd_subscribe categories=’depression’ placeholder=’Email Address’ button_text=’Subscribe Now for any new posts on the topic “DEPRESSION”‘]
Receive an email update when we add a new DEPRESSION article.
The Latest on: Depression
via Google News
The Latest on: Depression
- VIDEO: Manage sleep care in patients with depression, anxietyon May 28, 2022 at 8:14 am
The American Psychiatric Association added a clinical update track on sleep this year, according to Eric R. Williams, MD, of the University of South Carolina's School of Medicine. “The reason we are ...
- Lyft Co-Founder John Zimmer Reveals 'Overwhelming' Stress Led to 'Cycling of Bad Thoughts' and Depressionon May 27, 2022 at 12:29 pm
The president of the popular ridesharing app — who is on a mission to destigmatize depression after overcoming the condition — is speaking out as part of Mental Health Awareness Month ...
- Jovial Reveals Her Battle With Depressionon May 27, 2022 at 2:34 am
Juliet Mirriam Ayub popularly known by her stage name Jovial has come out to reveal how she battled with depression towards the end of last year. The Jeraha singer posted on her Instagram story how ...
- Antipsychotic Safe, Effective for Resistant Depression in Phase 3 Trialon May 26, 2022 at 8:54 am
The atypical antipsychotic cariprazine, which is approved for schizophrenia and bipolar disorder, is also effective as an adjunct treatment for resistant depression, results of a new phase 3 trial ...
- How To Know When It's Time To Take Medication For Depressionon May 26, 2022 at 2:45 am
There's no shame in taking a prescription for your mental health. Here are the signs you should ask about an antidepressant.
- MindScape Ketamine & Infusion Therapy Is Seeking Patients For A Depression-Focused Clinical Studyon May 25, 2022 at 9:47 am
Houston, Texas - MindScape Ketamine & Infusion Therapy from Houston, TX, is asking applicants suffering from depression to sign up for its no-fee clinical study. It is the only clinic in Houston to ...
- Cutting Edge: TMS treatment is safe, eases depression just like medication, says experton May 24, 2022 at 10:07 am
Since 2016, PGIMER has been using novel techniques such as TMS and Transcranial Direct Current Stimulation (TDCS) for the treatment of psychiatric, neurological and ENT conditions.
- Mental Health Matters: It's OK to talk about depression. It could save a life.on May 23, 2022 at 5:00 am
People are talking about mental illness, and the more we normalize it, the more we chip away at misconceptions and misinformation.
- Depression, loneliness associated with increased hospitalization risk after COVID-19on May 20, 2022 at 7:17 am
People who reported in a survey that they felt worried, depressed or lonely had a greater chance of being hospitalized after a COVID-19 diagnosis, suggests a study funded by the National Institutes of ...
via Bing News