Tiny magnetic particles from air pollution have for the first time been discovered to be lodged in human brains– and researchers think they could be a possible cause of Alzheimer’s disease.
Researchers at Lancaster University found abundant magnetite nanoparticles in the brain tissue from 37 individuals aged three to 92-years-old who lived in Mexico City and Manchester. This strongly magnetic mineral is toxic and has been implicated in the production of reactive oxygen species (free radicals) in the human brain, which are associated with neurodegenerative diseases including Alzheimer’s disease.
Professor Barbara Maher, from Lancaster Environment Centre, and colleagues (from Oxford, Glasgow, Manchester and Mexico City) used spectroscopic analysis to identify the particles as magnetite. Unlike angular magnetite particles that are believed to form naturally within the brain, most of the observed particles were spherical, with diameters up to 150 nm, some with fused surfaces, all characteristic of high-temperature formation – such as from vehicle (particularly diesel) engines or open fires.
The spherical particles are often accompanied by nanoparticles containing other metals, such as platinum, nickel, and cobalt.
Professor Maher said: “The particles we found are strikingly similar to the magnetite nanospheres that are abundant in the airborne pollution found in urban settings, especially next to busy roads, and which are formed by combustion or frictional heating from vehicle engines or brakes.”
Other sources of magnetite nanoparticles include open fires and poorly sealed stoves within homes. Particles smaller than 200 nm are small enough to enter the brain directly through the olfactory nerve after breathing air pollution through the nose.
“Our results indicate that magnetite nanoparticles in the atmosphere can enter the human brain, where they might pose a risk to human health, including conditions such as Alzheimer’s disease,” added Professor Maher.
Leading Alzheimer’s researcher Professor David Allsop, of Lancaster University’s Faculty of Health and Medicine, said: “This finding opens up a whole new avenue for research into a possible environmental risk factor for a range of different brain diseases.”
The Latest on: Magnetite nanoparticles
via Google News
The Latest on: Magnetite nanoparticles
- Magnetic Polymer Market is Estimated to Reach US$ 66.1 Mn by 2031, TMR Reporton August 4, 2022 at 6:30 pm
The magnetic polymer market is estimated to expand at a CAGR of 8.1% during the forecast period from 2022 to 2031. Wide industrial applications of magnetic polymers due to a range of favorable ...
- New research uses magnetic nanoparticles to manipulate genomic locion August 4, 2022 at 3:15 am
An innovative new technique manipulates specific genomic loci using magnetic nanoparticles, revealing chromatin has fluid-like properties ...
- A new step towards using magnetic bacteria in cancer treatmenton August 2, 2022 at 8:39 am
International research in which the UPV/EHU’s Magnetism and Magnetic Materials group is collaborating has succeeded in individually characterising ...
- Magnetic Activation of Specific Brain Circuitson July 28, 2022 at 5:00 pm
The researchers inject magnetic nanoparticles into the flies and then cause them to heat up using magnetic fields. This heat activates the ion channels and the neurons in which they are present ...
- CD Bioparticles Launches Ni-NTA Particles for His-tagged Protein Purificationon July 27, 2022 at 2:45 pm
With years of experience in the pharmaceutical and life science sector, CD Bioparticles launched a full product line of Ni-NTA Particles for use in His-tagged protein purification, including Ni-NTA ...
- Antitumor Immunity by Magnetic Nanoparticle-Mediated Hyperthermiaon July 23, 2022 at 5:00 pm
20] NPrCAP-conjugated magnetic nanoparticle 10 nm Targets melanoma cells and exerts chemotherapeutic effects [21–23] Antibody-conjugated magnetic nanoparticle 20 nm Targets human breast cancer ...
- Magnetite Nanoparticles Applications Growing Popularity and Emerging Trends to 2027on July 18, 2022 at 11:09 pm
According to the latest survey, the global magnetite nanoparticles market size is expected to exhibit at USD 112.43 million with the highest CAGR of 10.9% during the forecast period 2020-2027.
- These bacterial microrobots can kill cancer without causing any pain and tearson July 18, 2022 at 1:30 pm
By modifying E. coli bacteria using magnetic nanoparticles and nanoliposomes, scientists have found a bacteria-mediated treatment method that could kill cancer tumors grown inside a human body.
- Bacteria-Based Biohybrid Microrobots Could Help Fight Canceron July 18, 2022 at 9:47 am
Bacterial biohybrids carrying nanoliposomes (200 nm) and magnetic nanoparticles (100 nm). Nanoliposomes are loaded with chemotherapeutic DOX and photothermal agent ICG, and both cargoes are conjugated ...
via Bing News