Drugs researcher David Nutt discusses brain-imaging studies with hallucinogens.
Researchers have published the first images showing the effects of LSD on the human brain, as part of a series of studies to examine how the drug causes its characteristic hallucinogenic effects.
David Nutt, a neuropsychopharmacologist at Imperial College London who has previously examined the neural effects of mind-altering drugs such as the hallucinogen psilocybin, found in magic mushrooms, was one of the study’s leaders. He tells Nature what the research revealed, and how he hopes LSD (lysergic acid diethylamide) might ultimately be useful in therapies.
Why study the effects of LSD on the brain?
For brain researchers, studying how psychedelic drugs such as LSD alter the ‘normal’ brain state is a way to study the biological phenomenon that is consciousness.
We ultimately would also like to see LSD deployed as a therapeutic tool. The idea has old roots. In the 1950s and 60s thousands of people took LSD for alcoholism; in 2012, a retrospective analysis of some of these studies suggested that it helped cut down on drinking. Since the 1970s there have been lots of studies with LSD on animals, but not on the human brain. We need that data to validate the trial of this drug as a potential therapy for addiction or depression.
Why hasn’t anyone done brain scans before?
Before the 1960s, LSD was studied for its potential therapeutic uses, as were other hallucinogens. But the drug was heavily restricted in the UK, the United States and around the world after 1967 — in my view, due to unfounded hysteria over its potential dangers. The restrictions vary worldwide, but in general, countries have insisted that LSD has ‘no medical value’, making it tremendously difficult to work with.
How did you get approval to give volunteers LSD?
United Nations conventions and national laws do permit academic research on heavily-restricted drugs such as LSD. In the UK, this sort of study is legal so long as the drug is not being used as a therapeutic. This was not a clinical trial: we gave LSD to volunteers who were already experienced with the drugs and took their brain scans over eight hours in the lab in Cardiff, in 2014. It took us nine months to get approval from a UK ethics committeefor the work: the research was funded by the Safra Foundation [a philanthropic foundation in Geneva, Switzerland] and the Beckley Foundation [a charity near Oxford, UK, that promotes drug-policy reform] though we needed to crowdfund through Walacea.com for the resources to analyse the data.
What were the results of the study?
To take advantage of the “long trip” produced by LSD — an eight-hour experience, compared to say four on psilocybin — we put our participants through a huge range of tests.
Learn more: Brain scans reveal how LSD affects consciousness
The Latest on: LSD
via Google News
The Latest on: LSD
- Ellensburg Police arrest the man who gave Darin Cole LSD before his death in 2020on October 11, 2021 at 5:54 pm
ELLENSBURG, WA - Ellensburg Police Officers arrested 24-year-old Sedro Woolley Thursday, October 7th, for the delivery of a controlled substance and controlled substance homicide of the death of Darin ...
- Primal Scream's Bobby Gillespie tells of terrifying LSD trip near East Kilbrideon October 11, 2021 at 6:30 am
The Primal Scream rocker talks about his spell in The Jesus and Mary Chain in the mid 80s and claims he shared LSD with them in a disused factory just outside East Kilbride.
- Limited Slip Differential (LSD) Market 2021: Growth Prospects, Latest Trends, Industry Share, Development Strategy and Forecast to 2026on October 11, 2021 at 1:25 am
Get a Sample Copy of the Report - Market Analysis and Insights: Global Limited Slip Differential (LSD) Market The Limited Slip Differential (LSD) market revenue was Million USD in 2016, grew to ...
- SB DuSable Lake Shore Drive bridge repair work at McFetridge Dr. complete: CDOTon October 9, 2021 at 12:40 pm
NotifyChicago: 3 SB lanes to close on DuSable LSD at McFetridge Dr south of Roosevelt due to precautionary bridge repairs. Expect delays, seek alternate route. — Chicago OEMC (@ChicagoOEMC ...
- Overnight traffic stop in Kenosha nets Fentanyl, LSDon October 7, 2021 at 11:50 am
A traffic stop in Kenosha overnight Monday, Oct. 4, netted Fentanyl, LSD, THC, and drug money. Police said in a Facebook post, during third shift Monday night, 7 lbs. of THC wa ...
- From The Beatles to The Grateful Dead: Seven classic songs inspired by LSDon October 6, 2021 at 4:00 am
From The Beatles to Drake and everyone in between, nothing is off-limits for music. Writing songs about drugs and taking narcotics used to be a covert operation. To create a track about one’s penchant ...
- The Flaming Lips: Mother I’ve Taken LSD | The Tonight Show Starring Jimmy Fallonon September 30, 2021 at 9:33 pm
The Flaming Lips perform "Mother I’ve Taken LSD" for The Tonight Show. The Tonight Show Starring Jimmy Fallon. Stream now on Peacock: Subscribe NOW to The Tonight Show Starring Jimmy Fallon: Watch ...
- What is LSD? What to know about the drug's use among teens after car accident in Salemon September 30, 2021 at 6:13 pm
Health officials and law enforcement have a warning for parents about teen LSD use following a car accident in Henry County earlier in September.
- Can Psychedelic Drugs Treat Physical Pain?on September 30, 2021 at 4:31 am
But what about pain relief? That is the question a growing number of researchers are asking, based on anecdotal reports that drugs such as LSD or psilocybin can help with this. Both drugs are ...
- Scotland Decriminalizes Possession Of Class A Drugs (Cocaine, Heroin, LSD, MDMA, Shrooms) Amid A Drug Death Crisison September 28, 2021 at 3:29 pm
By Franca Quarneti via El Planteo In Scotland, possession of Class A drugs was effectively decriminalized. This classification includes cocaine, heroin, LSD, MDMA, and hallucinogenic mushrooms. What ...
via Bing News