A few years from now millions of people around the world might be walking around with an unusual kind of glass in their mouth, and using it every time they eat.
Engineers at Oregon State University have made some promising findings about the ability of “bioactive” glass to help reduce the ability of bacteria to attack composite tooth fillings – and perhaps even provide some of the minerals needed to replace those lost to tooth decay.
Prolonging the life of composite tooth fillings could be an important step forward for dental treatment, the researchers say, since more than 122 million composite tooth restorations are made in the United States every year. An average person uses their teeth for more than 600,000 “chews” a year, and some studies suggest the average lifetime of a posterior dental composite is only six years.
The new research was just published in the journal Dental Materials, in work supported by the National Institutes of Health.
“Bioactive glass, which is a type of crushed glass that is able to interact with the body, has been used in some types of bone healing for decades,” said Jamie Kruzic, a professor and expert in advanced structural and biomaterials in the OSU College of Engineering.
“This type of glass is only beginning to see use in dentistry, and our research shows it may be very promising for tooth fillings,” he said. “The bacteria in the mouth that help cause cavities don’t seem to like this type of glass and are less likely to colonize on fillings that incorporate it. This could have a significant impact on the future of dentistry.”
Bioactive glass is made with compounds such as silicon oxide, calcium oxide and phosphorus oxide, and looks like powdered glass. It’s called “bioactive” because the body notices it is there and can react to it, as opposed to other biomedical products that are inert. Bioactive glass is very hard and stiff, and it can replace some of the inert glass fillers that are currently mixed with polymers to make modern composite tooth fillings.
“Almost all fillings will eventually fail,” Kruzic said. “New tooth decay often begins at the interface of a filling and the tooth, and is called secondary tooth decay. The tooth is literally being eroded and demineralized at that interface.”
Bioactive glass may help prolong the life of fillings, researchers say, because the new study showed that the depth of bacterial penetration into the interface with bioactive glass-containing fillings was significantly smaller than for composites lacking the glass.
Fillings made with bioactive glass should slow secondary tooth decay, and also provide some minerals that could help replace those being lost, researchers say. The combination of these two forces should result in a tooth filling that works just as well, but lasts longer.
Recently extracted human molars were used in this research to produce simulated tooth restoration samples for laboratory experiments. OSU has developed a laboratory that’s one of the first in the world to test simulated tooth fillings in conditions that mimic the mouth.
If this laboratory result is confirmed by clinical research, it should be very easy to incorporate bioactive glass into existing formulations for composite tooth fillings, Kruzic said.
The antimicrobial effect of bioactive glass is attributed, in part, to the release of ions such as those from calcium and phosphate that have a toxic effect on oral bacteria and tend to neutralize the local acidic environment.
“My collaborators and I have already shown in previous studies that composites containing up to 15 percent bioactive glass, by weight, can have mechanical properties comparable, or superior to commercial composites now being used,” Kruzic said.
The Latest on: Bioactive glass
[google_news title=”” keyword=”bioactive glass” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]
via Google News
The Latest on: Bioactive glass
- Bioactive composite supports healing of broken boneson November 30, 2023 at 2:26 am
Its aim is to inhibit the growth of bacteria at the wound site and support the growth of new bone structures. This innovative medical engineering is the result of the SCABAEGO joint research project, ...
- Modification of titanium orthopedic implants with bioactive glass: a systematic review of in vivo and in vitro studieson November 14, 2023 at 4:00 pm
Surface modification of titanium alloys with bioactive glass can effectively combine the superior mechanical properties of the substrate with the biological properties of the coating material. In this ...
- Scientists develop healing scaffold that biodegrades into broken boneson November 10, 2023 at 5:27 am
The team in the research project, called SCABAEGO (Scaffold Bioactive Glass-Enhanced Osteogenesis), has developed a scaffold, a temporary structure, to support broken bones. Made of biodegradable ...
- Bioactive glass could be used to treat bone canceron July 7, 2023 at 12:41 pm
Materials engineer Geovana Lira Santana, from the state of Paraíba, discovered the properties of F18, a bioactive glass capable of stimulating bone regeneration, when she arrived at the Federal ...
- Bioactive Glass Marketon September 3, 2021 at 6:24 am
Bioactive glasses are a group of surface reactive glass-ceramic biomaterials that includes the original bioactive glass, bioglass. Biocompatibility and bioactivity of these glasses have led them to be ...
- Bioactive Glass Cleared for Postero-Lateral Fusionon November 16, 2015 at 4:00 pm
The FDA has granted clearance to Prosidyan, Inc.'s fiber-based bioactive glass products for use in postero-lateral fusion. The company’s Fibergraft BG Morsels, ultra-porous bone graft substitutes, are ...
via Bing News