“Polyol-Silk Bioink Formulations as Two-Part Room-Temperature Curable Materials for 3D Printing”
Advances in 3-D printing have led to new ways to make bone and some other relatively simple body parts that can be implanted in patients. But finding an ideal bio-ink has stalled progress toward printing more complex tissues with versatile functions — tissues that can be loaded with pharmaceuticals, for example. Now scientists, reporting in the journal ACS Biomaterials Science & Engineering, have developed a silk-based ink that could open up new possibilities toward that goal.
Most inks currently being developed for 3-D printing are made of thermoplastics, silicones, collagen and gelatin or alginate. But there are limits to how these inks can be used. For example, the temperatures, pH changes and crosslinking methods that may be required to toughen some of these materials can damage cells or other biological components that researchers would want to add to the inks. Additives, such as cytokines and antibiotics, are useful for directing stem cell functions and controlling infections, respectively. To address these bio-ink limitations, David L. Kaplan and colleagues turned to silk protein and developed a way to avoid these harsh processing conditions.
The researchers combined silk proteins, which are biocompatible, and glycerol, a non-toxic sugar alcohol commonly found in food and pharmaceutical products. The resulting ink was clear, flexible, stable in water, and didn’t require any processing methods, such as high temperatures, that would limit its versatility. The researchers say the novel material could potentially be used in biomedical implants and tissue engineering.
The Latest on: Bio-ink
via Google News
The Latest on: Bio-ink
- Biocept, Aegea Bio Ink COVID-19 Test Supply Agreementon March 2, 2021 at 9:14 am
Biocept entered into a supply agreement with Aegea Biotechnologies for a new PCR-based Covid-19 assay kit. Shares of Biocept fell 1.2% in midday US trading. Under the terms of the agreement, Aegea ...
- AstraZeneca, Junshi Bio collaborate to commercialize toripalimab in Chinaon February 28, 2021 at 8:36 pm
Junshi Biosciences grants AstraZeneca (AZN) exclusive promotion rights of toripalimab in mainland China for the urothelial carcinoma indications and for all indications ...
- US company wants to make 3D bio-ink printed meat for human consumptionon February 25, 2021 at 4:00 pm
The bio-ink particles can be reproducibly prepared with mixtures of cells of different type. Printing ensures consistent shape, while post-printing structure formation and maturation in the ...
- 3D Printing Materials Market Price Analysis 2021, Size, Share and Global Business Opportunities to 2027on February 24, 2021 at 4:50 am
The global3D printing materials marketsize is projected to reach USD 3.78 billion by 2026, exhibiting a CAGR of ...
- With Singapore giving the green-light to lab-grown meat, when will it hit American restaurants?on February 17, 2021 at 12:57 pm
The cells are placed in a centrifuge that separates them from excess materials • The cells are mixed with “a nutritious liquid called bio-ink” and are then formed into the desired shape by a ...
- Scientific Research And Development Services Global Market Report 2021: COVID 19 Impact and Recovery to 2030on February 17, 2021 at 2:09 am
For example, printed micro tissue from bio ink can undergo maturation via cellular coating to form functional tissue constructs such as engineered tissue constructs. Major biotechnology research ...
- Researchers Achieve First 3D Printing of Human Corneason February 15, 2021 at 3:59 pm
Key to the achievement by scientists at Newcastle University is a novel bio-ink—a gel comprised of alginate, a polysaccharide derived from seaweed, and collagen, the main structural protein in cornea.
- Handheld 3D Printer Could Be Game Changer in Burn and Trauma Careon February 11, 2021 at 4:00 pm
A new handheld 3D printer that looks sort of like a packing tape dispenser can apply sheets of skin to cover large burn wounds, and its “bio ink” can accelerate the healing process, according to ...
- ‘Bio-ink’ could form a scaffold for growing human tissueon February 11, 2021 at 4:00 pm
A “bio-ink” for 3D-printed materials could serve as scaffolds for growing human tissues to repair or replace damaged ones in the body, say bioengineers. Bioengineered tissues show promise in ...
- New Method Prints 3D Bones Using Living Cellson January 30, 2021 at 8:56 am
This new innovation can be performed at room temperature which is a first. The team created a 'bio-ink' gel that contains the patient's living bone cells in a calcium phosphate solution.
via Bing News