via BBC.com
Scientists say they are a step closer to growing fully functioning replacement kidneys, after promising results in animals.
When transplanted into pigs and rats, the kidneys worked, passing urine just like natural ones.
Getting the urine out has been a problem for earlier prototypes, causing them to balloon under the pressure.
The Japanese team got round this by growing extra plumbing for the kidney to stop the backlog, PNAS reports.
Although still years off human trials, the research helps guide the way towards the end goal of making organs for people, say experts.
In the UK, more than 6,000 people are waiting for a kidney – but because of a shortage of donors, fewer than 3,000 transplants are carried out each year.
More than 350 people die a year, almost one a day, waiting for a transplant.
Growing new kidneys using human stem cells could solve this problem.
Scientists say they are a step closer to growing fully functioning replacement kidneys, after promising results in animals.
When transplanted into pigs and rats, the kidneys worked, passing urine just like natural ones.
Getting the urine out has been a problem for earlier prototypes, causing them to balloon under the pressure.
The Japanese team got round this by growing extra plumbing for the kidney to stop the backlog, PNAS reports.
Although still years off human trials, the research helps guide the way towards the end goal of making organs for people, say experts.
In the UK, more than 6,000 people are waiting for a kidney – but because of a shortage of donors, fewer than 3,000 transplants are carried out each year.
More than 350 people die a year, almost one a day, waiting for a transplant.
Growing new kidneys using human stem cells could solve this problem.
Read more: Lab-grown kidneys work in animals
The Latest on: Growing human organs
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via Google News
The Latest on: Growing human organs
- In a 1st, scientists grow human kidneys inside developing pig embryoson September 11, 2023 at 11:44 am
Scientists grew early-stage human kidneys inside pig embryos and found the kidneys were "structurally normal" and made up of around 60% human cells.
- Scientists Grow Part-Human Kidneys in Pig Embryos for Nearly a Monthon September 11, 2023 at 9:05 am
The new work is a "big step forward" in finding new ways to generate viable organs for human transplants, but it comes with some ethical considerations ...
- Pigs and human organs: The groundbreaking study setting the science world alighton September 8, 2023 at 10:18 am
Rat organs have been produced in mice, and mouse organs have been produced in rats, but previous attempts to grow human organs in pigs have not succeeded,” senior study author Liangxue Lai, a ...
- Scientists Just Tried Growing Human Kidneys in Pigson September 8, 2023 at 4:00 am
For now, scientists are still a long way from growing a fully human organ inside a pig. “Humans diverged from pigs about 80 million years ago, so growing human cells in a pig embryo is a ...
- Scientists take ‘pioneering steps’ toward growing human kidneys in pigson September 7, 2023 at 3:30 pm
Scientists have grown kidneys containing mostly human cells inside pig embryos, an important step toward growing kidneys and potentially other human organs that could be used for transplants in people ...
- Scientists Say They've Now Grown a Whole Human Embryo Model From Scratchon September 7, 2023 at 12:10 pm
A team of scientists in Israel say they’ve created a completely human-like embryo model without the need for a sperm or egg, up through 14 days of development.
- Scientists Grow Human-like Kidneys In Pigson September 7, 2023 at 12:07 pm
Chinese scientists have succeeded in growing kidneys containing human cells in pig embryos, a world first that could one day help address organ donation shortages.
- Scientists grow human kidneys inside PIGS for 28 days - in a breakthrough that could revolutionise organ transplantson September 7, 2023 at 8:59 am
The holy grail to prevent thousands of people from dying while waiting for a transplant is to grow human organs in animals, creating a limitless supply without having to wait for human organ donors.
- In a First, Scientists Grow Human Kidneys Inside Pigson September 7, 2023 at 8:01 am
Chinese researchers grew partially human early-stage kidneys inside embryonic pigs, using a variety of genetic engineering techniques, a new report reveals.
- Human kidneys have been partially grown in pigs for the first timeon September 7, 2023 at 8:00 am
Early kidney structures made of mostly human cells have been grown in pig embryos for up to 28 days as part of efforts to grow human organs in other animals for transplants ...
via Bing News
