Recent research published in the journal Microsystems & Nanoengineering could eventually change the way people living with prosthetics and spinal cord injury lead their lives.
Instead of using neural prosthetic devices—which suffer from immune-system rejection and are believed to fail due to a material and mechanical mismatch—a multi-institutional team, including Lohitash Karumbaiah of the University of Georgia’s Regenerative Bioscience Center, has developed a brain-friendly extracellular matrix environment of neuronal cells that contain very little foreign material. These by-design electrodes are shielded by a covering that the brain recognizes as part of its own composition.
Although once believed to be devoid of immune cells and therefore of immune responses, the brain is now recognized to have its own immune system that protects it against foreign invaders.
“This is not by any means the device that you’re going to implant into a patient,” said Karumbaiah, an assistant professor of animal and dairy science in the UGA College of Agricultural and Environmental Sciences. “This is proof of concept that extracellular matrix can be used to ensheathe a functioning electrode without the use of any other foreign or synthetic materials.”
Implantable neural prosthetic devices in the brain have been around for almost two decades, helping people living with limb loss and spinal cord injury become more independent. However, not only do neural prosthetic devices suffer from immune-system rejection, but most are believed to eventually fail because of a mismatch between the soft brain tissue and the rigid devices.
The collaboration, led by Wen Shen and Mark Allen of the University of Pennsylvania, found that the extracellular matrix derived electrodes adapted to the mechanical properties of brain tissue and were capable of acquiring neural recordings from the brain cortex.
“Neural interface technology is literally mind boggling, considering that one might someday control a prosthetic limb with one’s own thoughts,” Karumbaiah said.
The study’s joint collaborators were Ravi Bellamkonda, who conceived the new approach and is chair of the Wallace H. Coulter Department of Biomedical Engineering at the Georgia Institute of Technology and Emory University, as well as Allen, who at the time was director of the Institute for Electronics and Nanotechnology.
“Hopefully, once we converge upon the nanofabrication techniques that would enable these to be clinically translational, this same methodology could then be applied in getting these extracellular matrix derived electrodes to be the next wave of brain implants,” Karumbaiah said.
Currently, one out of every 190 Americans is living with limb loss, according to the National Institutes of Health. There is a significant burden in cost of care and quality of life for people suffering from this disability.
The Latest on: Neuroprosthetics
[google_news title=”” keyword=”neuroprosthetics” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]
via Google News
The Latest on: Neuroprosthetics
- Bio-Inspired Neuroprosthetics: Sending Signals The Brain Can Understand Robotics & Automation Newson February 22, 2024 at 8:13 pm
Now, researchers at ETH Zurich have found evidence that neuroprosthetics work better when they use signals that are inspired by nature. A few years ago, a team of researchers working under Professor ...
- Nature-inspired biomimetic stimulation powers next-gen neuroprostheticson February 22, 2024 at 1:44 pm
A team of researchers at ETH Zurich found evidence that neuroprosthetics work better when they use signals that are inspired by nature.
- Goodbye robotic jerks: Bio-prosthetics learn the brain’s codeon February 22, 2024 at 4:38 am
Explore the cutting-edge research on bio-inspired neuroprosthetics, paving the way for enhanced prosthetic technology.
- Bio-inspired neuroprosthetics: Sending signals the brain can understandon February 21, 2024 at 6:34 am
A few years ago, a team of researchers working under Professor Stanisa Raspopovic at the ETH Zurich Neuroengineering Lab gained worldwide attention when they announced that their prosthetic legs had ...
- Bio-inspired neuroprosthetics: sending signals the brain can understandon February 20, 2024 at 4:00 pm
ETH Zurich researchers together with colleagues in Germany, Serbia and Russia have proposed that neuroprosthetics should transmit biomimetic signals that are easier for the brain to understand. These ...
- Neuroprosthetics Market Size Worth USD 33.96 Billion In 2032 | Emergen Researchon January 29, 2024 at 4:14 am
Neuroprosthetics are devices that can improve the input and output of neural system. These devices make use of direct electrical impulse for stimulating the nervous system and improving its ...
- Neuroprosthetics market Size Worth USD 33.96 Billion in 2032 | Emergen Researchon January 29, 2024 at 4:00 am
Vancouver, Jan. 29, 2024 (GLOBE NEWSWIRE) -- The global neuroprosthetics market size was USD 10.48 Billion in 2022 and is expected to register a rapid revenue CAGR of 12.4% during the forecast period.
- Artículos sobre Neuroprostheticson September 1, 2020 at 1:33 pm
From warfare to entertainment and VR, brain-computer interface development has extended beyond prosthetics for patients with disabilities. Missing is full ethical consideration of the consequences ...
via Bing News