via www.medgadget.com
To help address the global obesity epidemic, scientists are developing a new class of compounds called “micelle sequestrant polymers,” or MSPs, that could prevent fat particles from getting absorbed in the body and thus potentially reduce weight gain. They report on their novel agents, which they tested on mice, in the ACS journal Biomacromolecules.
Research has shown that worldwide, obesity rates have been climbing for years. Treatments for overweight and obesity include diet and exercise, surgery and prescription medications. But currently available drugs can have serious side effects, including increased risk of cardiovascular disease and depression. So Cory Berkland and colleagues set out to find new kinds of pharmaceuticals to fight weight gain.
Targeting the body’s process of absorbing fat, the researchers designed a class of polymers that capture fat particles called micelles in the intestines so they can’t be digested. Instead, they pass through the gut and are excreted. In tests, mice who took these MSPs had nine to 10 times the amount of triglycerides — the main dietary fat — in their feces than the control animals. Additionally, because the MSPs pass through the body unabsorbed, the researchers say they could provide a safe approach for long-term treatment.
The Latest on: Antiobesity Drug
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The Latest on: Antiobesity Drug
- Weight loss startup Noom launches program prescribing new weight loss drugs like Wegovyon June 2, 2023 at 8:44 pm
WeightWatchers:WeightWatchers is adding next-generation weight loss drugs like Wegovy to its program Obesity ... the stomach and the brain indicating fullness – and other anti-obesity medications ...
- People probably have to be on Ozempic forever. But no one is ready for the bill.on June 2, 2023 at 4:00 am
The weight-loss drugs are probably lifelong medications, but some employers and prescriptions startups are reluctant to approach them this way.
- Obesity drugs help patients lose weight regained years after bariatric surgeryon June 1, 2023 at 1:54 pm
Anti-obesity medications, including semaglutide (Ozempic and Wegovy), can effectively help patients manage weight regained after bariatric surgery, a study led by UT Southwestern Medical Center ...
- Medical Council warns doctors against using diabetes drug for weight losson May 31, 2023 at 9:00 pm
Doctors have been warned about prescribing a scarce new diabetes drug to treat obesity.
- Global obesity drugs sales could top $44bn in 2030, says Bloomberg Intelligenceon May 31, 2023 at 6:50 am
Sales of branded anti-obesity drugs (AOB) could hit $44 billion in 2030 vs. $2.5 billion in 2022, with just under 70% stemming from the US, according to a report from Bloomberg Intelligence.
- Weight loss startup Noom launches program prescribing new weight loss drugs like Wegovyon May 25, 2023 at 2:31 am
WeightWatchers:WeightWatchers is adding next-generation weight loss drugs like Wegovy to its program ... brain indicating fullness – and other anti-obesity medications through the program.
- Medicare Coverage of Weight Loss Drugs May Reduce Access Disparitieson May 23, 2023 at 10:00 am
Given the substantial costs, Medicare coverage of weight loss drugs could lead to higher Medicare spending but may help reduce access disparities, according to a KFF policy watch.
- Game-changing obesity drugs go mainstream: what scientists are learningon May 23, 2023 at 9:47 am
A new generation of drugs is revolutionizing the treatment of obesity and astonishing researchers with their potency. The drug semaglutide, for example, enabled one-third of clinical-trial ...
- After One Year, Popular Weight Loss Drug Semaglutide (Wegovy/Ozempic) Improved Heart Healthon May 22, 2023 at 9:58 am
A small study found that the popular weight loss drug semaglutide may help lower the risk of developing cardiovascular disease. After one year, study participants showed improvements in multiple ...
- Medicare is prohibited from paying for weight-loss drugs. These are the 3 potential ways to change that.on May 22, 2023 at 6:00 am
Medicare is barred by law from paying for drugs for weight loss such as Ozempic and Wegovy. Expanding coverage could be costly, but it could also help Medicare save money over time. There are three ...
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