CNPMicrocapsule
via Queen Mary University of London
A new ‘microcapsule’ treatment delivery method developed by researchers at Queen Mary University of London (QMUL) could reduce inflammation in cartilage affected by osteoarthritis and reverse damage to tissue.
The research was funded by Arthritis Research UK and the AO Foundation.
A protein molecule called C-type natriuretic peptide (CNP), which occurs naturally in the body, is known to reduce inflammation and aid in the repair of damaged tissue. However, CNP cannot be used to treat osteoarthritis in patients because it cannot target the damaged area even when the protein is injected into the cartilage tissue. This is because CNP is easily broken down and cannot reach the diseased site.
The researchers constructed tiny microcapsules, just 2 microns in diameter, with individual layers containing CNP that could release the protein slowly and therefore deliver the treatment in the most effective way.
In experiments on samples of cartilage taken from animals, they showed that the microcapsules could deliver the anti-inflammatory CNP in a highly effective way. The researchers believe that injections of microcapsules could in the future be used to heal damaged cartilage in people with osteoarthritis. The injections could be delivered easily by a GP.
Dr Tina Chowdhury from QMUL’s School of Engineering and Materials Science, who leads the research, said:
“If this method can be transferred to patients it could drastically slow the progression of osteoarthritis and even begin to repair damaged tissue.
“CNP is currently available to treat other conditions such as skeletal diseases and cardiovascular repair. If we could design simple injections using the microcapsules, this means the technology has the potential to be an effective and relatively cheap treatment that could be delivered in the clinic or at home.”
Read more here: New ‘microcapsules’ have potential to repair damage caused by osteoarthritis
The Latest on: Microcapsules
via Google News
The Latest on: Microcapsules
- Salem students win first place in national science competitionon May 18, 2022 at 6:00 am
A group of Queen of Peace Catholic School third and fourth graders will get to present their winning idea to Bill Nye the Science Guy.
- Apple said to be testing coloured e-ink displays for a future foldable iPhoneon May 18, 2022 at 3:43 am
Apple is trialling the use of E Ink electronic colour paper displays for future devices, according to reputable analyst Ming-Chi Kuo. In a tweet, Kuo said the company is testing the technology for ...
- Sol-Gel Technologies Reports First Quarter 2022 Financial Results and Provides Corporate Updateon May 13, 2022 at 4:00 am
FDA approval for EPSOLAY® (benzoyl peroxide, cream, 5%) represents Sol-Gel’s second approved product within less than a year; EPSOLAY is patent protected until 2040Partner Galderma to launch two ...
- Antimated Quorum Sensing Behavior (IMAGE)on May 7, 2022 at 5:15 am
Modeled microcapsules demonstrate 'quorum sensing' behavior. A small collection of microcapsules remains dormant (left) whereas a large, crowded population exhibits oscillations in chemical ...
- Demonstrating Quorum Sensing Behavior (IMAGE)on May 7, 2022 at 5:15 am
Modeled microcapsules demonstrate 'quorum sensing' behavior. A small collection of microcapsules remains dormant (left) whereas a large, crowded population exhibits oscillations in chemical ...
- Advanced Manufacturing of Polymers & Soft Materialson April 27, 2022 at 5:27 am
Photoresist polymers for nanolithography, nanofluidic devices & microcapsules & hybrid nanoparticles for nanomedicine, biomedical devices, drug delivery devices and biosensors. Synthesis & ...
- FDA approves Epsolay cream for rosaceaon April 25, 2022 at 8:20 am
Epsolay, a cream formulation of benzoyl peroxide 5% encapsulated within silica-based microcapsules, is designed to slowly release the drug over time. The FDA has approved Epsolay cream for the ...
- Sol-Gel's stock rises as FDA approves Epsolay to treat skin condition rosaceaon April 25, 2022 at 12:37 am
The company said the benzoyl peroxide in Epsolay is encapsulated within silica-based patented microcapsules, which is designed to slowly release benzoyl peroxide over time. The company said the ...
- CRISPR nanocapsule limits growth of aggressive brain tumours in miceon April 20, 2022 at 11:54 am
which were given microcapsules containing either non-targeted genetic material or saline solution. What’s more, the new technique caused negligible – fewer than 0.5 per cent – unwanted ...
- Drug Discoveryon June 19, 2020 at 8:12 am
Eugenia Kharlampieva, Ph.D., and Veronika Kozlovskaya, Ph.D., in the Department of Chemistry are harnessing the potential of microcapsules for use in human and environmental health. The pair is ...
via Bing News
