Bone tissue regeneration – via Nature.com
Researchers in bone tissue regeneration believe they have made a significant breakthrough for sufferers of bone trauma, disease or defects such as osteoporosis.
Medical researchers from Keele University and Nottingham University have found that magnetic nanoparticles coated with targeting proteins can stimulate stem cells to regenerate bone. Researchers were also able to deliver the cells directly to the injured area, remotely controlling the nanoparticles to generate mechanical forces and maintain the regeneration process through staged releases of a protein growth stimulant.
The current method for repairing bone that can’t heal itself is through a graft taken from the patient. Unfortunately, this can be a painful, invasive procedure, and when the area that needs repair is too large or the patient has a skeletal disorder such as there can sometimes be a lack of healthy bone for grafting.
For this reason, spurring the growth of new bone through injected stem cells is an area of great interest to medical researchers. Much progress has been made, but a major hurdle remains – finding an appropriate means to stimulate the differentiation of the stem cells so they become the quality of bone tissue needed in a quantity large enough to treat patients effectively.
The Latest on: Bone regeneration
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The Latest on: Bone regeneration
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In natural regeneration, these growth factors ... "I work on bones, so when I see a problem, I look at the bone problem," he said. "People who work on nerves, all they look at are nerves.
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