via DARPA
Prototype’s novel approach uses magnetic nano-sized beads to filter deadly microbes and toxins from the bloodstream
Sepsis—a life-threatening over-reaction by the immune system to infection—afflicts 18 million people a year worldwide and kills between 30 and 50 percent of them. Sepsis poses a significant threat to warfighters who suffer combat injuries that predispose them to infection. Antibiotics can kill sepsis-inducing microbes but their overuse is contributing to the threat of drug-resistant microbes and they don’t neutralize the toxins that some pathogens leave behind. Commercial dialysis equipment can remove toxins from the blood but is not built for routine use in theater.
DARPA’s Dialysis-Like Therapeutics (DLT) program seeks to develop integrated, portable and ruggedized technology that would enable widespread deployment of dialysis treatment to fight sepsis. The program recently tested a novel prototype that could greatly advance sepsis treatment and lead to increased survival of future sepsis patients. As reported in Nature Medicine (http://ow.ly/BvJOm), the DLT program successfully demonstrated one of the first technologies for pathogen removal via blood filtration. With a design inspired by the human spleen, the shoebox-sized prototype removes many of the microbes and toxins that can trigger sepsis.
“Sepsis is a massive problem for both civilian and military healthcare, which is why DARPA set out to develop more effective and portable technologies for sepsis treatment,” said U.S.Army Col. Matt Hepburn, DARPA program manager. “Our ‘artificial spleen’ prototype shows a promising new way to fight sepsis more quickly and thoroughly. The technology is also small and light, and usable either on its own or with commercial dialysis equipment.”
Eventually, Hepburn added, DLT could preclude the need to fully identify a bacterium or test whether it is antibiotic resistant—which can take hours or days—before beginning treatment. “We’re hopeful that this new technology could give doctors new tools to save lives in the future,” he said.
The Latest on: Artificial spleen
via Google News
The Latest on: Artificial spleen
- Scientists find way to grow human organs in manipulated pigon August 4, 2022 at 5:00 pm
Kobayashi and his colleagues surgically removed the pig’s thymus gland and spleen, which produce T ... The researchers transplanted artificial blood vessels derived from human cells into the ...
- Immunologic Aspects of Organ Transplantationon July 26, 2022 at 5:00 pm
APCs carry foreign antigens that enter the host via the respiratory tract, GI tract, or skin through the lymphatic system and present them to lymphocytes in the lymph nodes and spleen, thereby ...
- Artificial Pancreas Systems Market Insights on the Important Factors and Trends Influencing the Industry with a CAGR of 8.40% By 2028on July 26, 2022 at 11:21 am
An analysis of competitors is conducted very well in the world class Artificial Pancreas Systems Market report which ...
- 30 Benefits of Turmeric in 2022on July 26, 2022 at 9:27 am
Supports spleen health Turmeric may help to support spleen health ... It is also free of synthetic fillers, artificial flavors, or colors. As you can see there are many benefits of turmeric. This list ...
- Pet Food Ingredient Market Size is projected to reach USD 77 Billion by 2030, growing at a CAGR of 7.2%: Straits Researchon July 12, 2022 at 10:03 am
Parts of damaged carcasses, bones, cheek meat, and organs including intestines, kidneys, liver, lungs, udders, spleen ... examples of liquid ingredients. Artificial flavors are not used in ...
- Madrigal Pharmaceuticals Presents Late-Breaking Phase 3 NASH Data and Multiple Oral Abstracts at EASL’s International Liver Congress™on June 25, 2022 at 4:28 pm
Spleen volume was also reduced and was strongly ... new insights to inform noninvasive testing strategies, improve artificial intelligence-based evaluation of treatment response, and better ...
- Madrigal Pharmaceuticals Presents Late-Breaking Phase 3 NASH Data and Multiple Oral Abstracts at EASL’s International Liver Congress™on June 25, 2022 at 2:00 am
Please enter a search term. Primary Menu News Sacramento Mass Shooting Local News Capitol to Capitol California Wildfire Watch ...
- Shamans, Software, and Spleens: Law and the Construction of the Information Societyon July 29, 2019 at 6:55 am
Might it be the doctors who, in the course of removing your spleen, decode a few cells and turn them into ... Discussing topics ranging from blackmail and insider trading to artificial intelligence ...
via Bing News