Cardiac optogenetics achieve defibrillation without the pain of electric shocks
The first evidence for a shockless treatment for atrial fibrillation (AF) will be presented today at Frontiers in CardioVascular Biology (FCVB) 2014 in Barcelona, Spain. The meeting is organised by the Council on Basic Cardiovascular Science of the European Society of Cardiology (ESC) in collaboration with 13 European cardiovascular science societies.http://spo.escardio.org/SessionDetails.aspx?eevtid=65&sessId=13104
Dr Brian O. Bingen, first author, said: “AF is the most common cardiac arrhythmia. Symptoms range from the feeling of fish flapping in the chest, to tiredness and exercise intolerance. AF can lead to tachycardia induced cardiomyopathy and thromboembolic events which increase the risk of morbidity and death.”
He added: “Preventing these symptoms and complications requires bringing the patient out of AF and back to the normal sinus rhythm. The quickest way to do that is to deliver an electric shock. The shock depolarises and synchronises the heart muscle and allows the sinus node to re-establish a normal rhythm.”
“This is the first evidence of a shockless defibrillation. Our method of using optogenetics to defibrillate by light is completely painless and looks promising but more research is needed before it can be applied in patients.”
Read more . . .
The Latest on: Cardiac optogenetics
via Google News
The Latest on: Cardiac optogenetics
- Neuroscience 2017on August 1, 2022 at 5:00 pm
Neuroscience aims to understand how a single organ can control the entire body, from immune response to heart rate, from movement to learning and feeling. Neuroscientists work within a much wider ...
- New Research Faculty Introductionon July 26, 2022 at 1:28 pm
Funding sources for early ICU rehabilitation have been the NIH's National Institute of Nursing Research and the National Heart Lung and Blood Institute ... pharmacology, and optogenetics and will use ...
- Unique technology platform at the MBExC Cluster of Excellence combines cellular electrophysiology and optogeneticson July 22, 2022 at 4:03 am
and MBExC optogenetics application specialist Dr. Thomas Mager from the Institute for Auditory Neuroscience at the UMG. The heart of the new platform is the MBExC-funded patch-clamp robot ...
- Eric Topol on Medscapeon July 20, 2022 at 5:00 pm
Ed Boyden and Optogenetics: The Future of Neuroscience ... Medscape, September 06, 2017 Kathiresan and Topol on Genomics of Heart Disease Eric Topol speaks with Sekar Kathiresan about ...
- Researchers Discover Novel Light-Gated Potassium Channel in Neuronson July 19, 2022 at 3:48 pm
One of the most popular approaches to controlling neuronal activity in model systems is called optogenetics and depends on expressing microbial light-gated channels in the neurons of interest. These ...
- Researchers discover novel light-gated potassium channel in neuronson July 19, 2022 at 5:49 am
One of the most popular approaches to controlling neuronal activity in model systems is called optogenetics and depends ... and long-QT syndrome and other cardiac arrhythmias.
- Robots Get Genetically Engineered Skeletal Muscleson July 17, 2022 at 4:59 pm
Instead, the researchers turned to optogenetics, which involves genetically modifying neurons so they respond to short light pulses. To date, optogenetic techniques had been used to stimulate cardiac ...
- T. Alexander Quinnon May 30, 2016 at 7:18 pm
Electrotonic coupling of excitable and nonexcitable cells in the heart revealed by optogenetics. Proc Natl Acad Sci U S A. 2016; 113:14852-7. Gemmell P, Burrage K, Rodriguez B, Quinn TA.
via Bing News