Cardiac optogenetics achieve defibrillation without the pain of electric shocks
The first evidence for a shockless treatment for atrial fibrillation (AF) will be presented today at Frontiers in CardioVascular Biology (FCVB) 2014 in Barcelona, Spain. The meeting is organised by the Council on Basic Cardiovascular Science of the European Society of Cardiology (ESC) in collaboration with 13 European cardiovascular science societies.http://spo.escardio.org/SessionDetails.aspx?eevtid=65&sessId=13104
Dr Brian O. Bingen, first author, said: “AF is the most common cardiac arrhythmia. Symptoms range from the feeling of fish flapping in the chest, to tiredness and exercise intolerance. AF can lead to tachycardia induced cardiomyopathy and thromboembolic events which increase the risk of morbidity and death.”
He added: “Preventing these symptoms and complications requires bringing the patient out of AF and back to the normal sinus rhythm. The quickest way to do that is to deliver an electric shock. The shock depolarises and synchronises the heart muscle and allows the sinus node to re-establish a normal rhythm.”
“This is the first evidence of a shockless defibrillation. Our method of using optogenetics to defibrillate by light is completely painless and looks promising but more research is needed before it can be applied in patients.”
The Latest on: Cardiac optogenetics
via Google News
The Latest on: Cardiac optogenetics
- Neuroscience 2017on August 25, 2021 at 5:00 pm
Neuroscience aims to understand how a single organ can control the entire body, from immune response to heart rate, from movement to learning and feeling. Neuroscientists work within a much wider ...
- Neuroscientist Karl Deisseroth: ‘Our understanding as human beings and animals comes from plants’on August 20, 2021 at 3:22 am
The psychiatrist and bioengineer pioneered the use of optogenetics, where light is used to control genetically modified neurons. He has just published a book about the history of emotion ...
- Doctoral candidate Aleks Klimas wins international biophotonics prizeon August 9, 2021 at 5:00 pm
Klimas works on optogenetics-aided high-throughput systems for cardiac electrophysiology. Aleks Klimas, a biomedical engineering doctoral candidate at The George Washington University's School of ...
- From CRISPR to glowing proteins to optogenetics – scientists' most powerful technologies have been borrowed from natureon August 5, 2021 at 6:42 am
Three cutting-edge techniques – the gene-editing tool CRISPR, fluorescent proteins and optogenetics – were all inspired by ... that causes fatal nerve and heart conditions. Preliminary results from ...
- From CRISPR to glowing proteins to optogenetics - scientists' most powerful technologies have been borrowed from natureon August 5, 2021 at 6:22 am
Three cutting-edge techniques – the gene-editing tool CRISPR, fluorescent proteins and optogenetics – were ... that causes fatal nerve and heart conditions. Preliminary results from the ...
- G212601 - Medicine - Cardiovascular Disease - Zhou Labon August 1, 2021 at 11:38 am
Loss of mitochondrial function has been implicated in the pathogenesis of heart failure; however ... 4) A background in optogenetics, while useful, is not essential. 5) The ideal candidate will be ...
- Robots Get Genetically Engineered Skeletal Muscleson July 28, 2021 at 5:00 pm
Instead, the researchers turned to optogenetics, which involves genetically modifying neurons so they respond to short light pulses. To date, optogenetic techniques had been used to stimulate cardiac ...
- Incredible New 3D Imaging Technique Provides New Way to Study Beating Hearts (VIDEO)on July 23, 2021 at 5:00 pm
They combined the imaging technique with optogenetics, a way of embedding genes that allow light to be used to turn certain processes on and off, to stop and start the zebrafish heart at will.
- Kimberly B. Bjugstad PhDon December 22, 2019 at 3:06 am
During her time as a research scientist, she has published more than 40 peer-reviewed articles and given over 75 conference presentations on topics including Alzheimer’s disease, heart disease, ...
via Bing News