Tweaking a protein expressed by most liver cancer cells has enabled scientists to make a vaccine that is exceedingly effective at preventing the disease in mice.
Alpha-Fetoprotein, or AFP – normally expressed during development and by liver cancer cells as well – has escaped attack in previous vaccine iterations because the body recognizes it as “self,” said Dr. Yukai He, immunologist at the Medical College of Georgia and Georgia Regents University Cancer Center.
Liver cancer is among the fastest-growing and deadliest cancers in the United States with a 17 percent three-year survival rate. Vaccines help direct the immune system to attack invaders by showing it a representative substance, called an antigen, that the body will recognize as foreign, in this case, AFP for liver cancer.
The Latest on: Liver cancer
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The Latest on: Liver cancer
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- Liver cancer symptoms: The sign in your stomach that could point to the diseaseon June 7, 2022 at 2:05 am
Cancer Research UK says this could be due to two reasons. Either “the liver gets bigger from the growing cancer, and causes swelling on the right side of your abdomen” or “the cancer (or ...
- Etiologies of liver cancer are changing and the prognosis is mixed, study sayson June 6, 2022 at 9:38 pm
The causes of liver cancer varied measurably around the world. Age-standardized death rates (ASDR) due to HBV-associated liver cancer decreased between 2010 and 2019, most likely due to successful ...
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