Scheme of mammalian target of rapamycin pathway_German translation (Photo credit: Wikipedia)
A proven approach to slow the aging process is dietary restriction, but new research in the Linus Pauling Institute at Oregon State University helps explain the action of a drug that appears to mimic that process – rapamycin.
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The Latest on: Rapamycin
via Google News
The Latest on: Rapamycin
- Protein anchors as a newly discovered key molecule in cancer spread and epilepsyon January 25, 2021 at 9:59 am
Certain anchor proteins inhibit a key metabolic driver that plays an important role in cancer and developmental brain disorders. Scientists from the German Cancer Research Center (DKFZ) and the ...
- A new mechanism protects against cancer cell migration and neuron hyperexcitabilityon January 25, 2021 at 8:17 am
G3BP proteins inhibit the metabolic driver MTOR - a signaling protein that plays a central role in tumor diseases and developmental disorders of the brain. This is reported in this week´s issue of the ...
- Stomach-specific c-Myc overexpression and gastric canceron January 22, 2021 at 6:50 am
Furthermore, AKT inhibitor (MK-2206) or mTOR inhibitor (Rapamycin) repressed the proliferation of c-Myc overexpressing gastric cancer cells and the gastric tumorigenesis in c-Myc transgenic mice.
- Everolimus for Advanced Pancreatic Neuroendocrine Tumorson January 20, 2021 at 4:00 pm
Everolimus, an oral inhibitor of mammalian target of rapamycin (mTOR), has shown antitumor activity in patients with advanced pancreatic neuroendocrine tumors, in two phase 2 studies. We evaluated ...
- Sirolimus for Kaposi's Sarcoma in Renal-Transplant Recipientson January 20, 2021 at 4:00 pm
Sirolimus (rapamycin), an immunosuppressive drug, may also have antitumor effects. We stopped cyclosporine therapy in 15 kidney-transplant recipients who had biopsy-proven Kaposi's sarcoma and ...
- New method reveals how pharmaceuticals induce cancer cell deathon January 19, 2021 at 5:47 pm
Cancer cells are smart when it comes to anti-cancer drugs, evolving and becoming resistant to even the strongest chemotherapies over time.
- Why Did This Cancer Metastasize to the Pancreas?on January 19, 2021 at 4:07 pm
The Memorial Sloan Kettering Cancer Center model for risk stratification of cancer advises that treatment selection be based on the type of malignancy, whether it is a CCRCC or non-CCRCC, and whether ...
- Single-cell test can reveal precisely how drugs kill cancer cellson January 19, 2021 at 9:23 am
Cancer cells are smart when it comes to anti-cancer drugs, evolving and becoming resistant to even the strongest chemotherapies over time. To combat this evasive behavior, researchers have developed a ...
- Sirolimus promising therapy for Lymphatic Malformations in kids, find MRI studieson January 17, 2021 at 4:00 am
Lymphatic malformations are abnormalities that arise in the developing lymphatic system, most frequently presenting in the head and neck. A recent study published in the American Journal ...
- Anti-Fibrotic Effects of Pirfenidone and Rapamycin in Primary IPF Fibroblasts and Human Alveolar Epithelial Cellson January 16, 2021 at 4:00 pm
After the cultures were established, we stimulated the cells with TGF−β (5 ng/ml), pirfenidone (1 mg/ml) and rapamycin (1 μg/ml). Besides the treatment of rapamycin and pirfenidone without TGF ...
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