English: Diagram of how microtubules desintegrate with Alzheimer’s disease Français : La protéine Tau dans un neurone sain et dans un neurone malade Español: Esquema que muestra cómo se desintegran los microtúbulos en la enfermedad de Alzheimer (Photo credit: Wikipedia)
Mechanism uncovered could also help preserve neuron function in Alzheimer’s disease, traumatic brain injury and other neurodegenerative conditions
Research presented by Dr. Lynn Raymond, from the University of British Columbia, shows that blocking a specific class of glutamate receptors, called extrasynaptic NMDA receptors, can improve motor learning and coordination, and prevent cell death in animal models of Huntington disease. As Huntington disease is an inherited condition that can be detected decades before any clinical symptoms are seen in humans, a better understanding of the earliest changes in brain cell (neuronal) function, and the molecular pathways underlying those changes, could lead to preventive treatments that delay the onset of symptoms and neurodegeneration. “After more than a decade of research on the pre-symptomatic phase of Huntington disease, markers are being developed to facilitate assessment of interventional therapy in individuals carrying the genetic mutation for Huntington disease, before they become ill. This will make it possible to delay onset of disease,” says Dr. Raymond.
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The Latest on: Huntington’s disease
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The Latest on: Huntington’s disease
- Documentary shows emotional visit between the Pope and people with Huntington's diseaseon May 15, 2021 at 2:05 am
That's why he made this documentary about Huntington's disease, a degenerative, painful and hereditary condition from which he himself suffers. “Because it doesn't matter how much money you have. With ...
- Two local woman using their own struggle to bring awareness about Huntington’s Diseaseon May 14, 2021 at 5:34 am
May is Huntington’s Disease Awareness Month. Huntington’s Disease, or HD, is a genetic brain disease that causes nerve cells in the brain to break down, deteriorating a person’s ...
- Propensity for somatic expansion increases over the course of life in Huntington diseaseon May 13, 2021 at 8:48 am
Somatic instability of the CAG repeat increases progressively with age and disease progression in Huntington disease mutation carriers, starting with low levels in fetal brain tissues.
- BioTek reMEDys Promotes Awareness and Education for Huntington’s Diseaseon May 12, 2021 at 12:39 pm
In honor of May being Huntington’s Disease Awareness Month, BioTek reMEDys, one of the nation’s largest independent specialty infusion pharmacies focused on rare diseases, is calling for enhanced ...
- Hoop-a-Thon for Huntington’s Diseaseon May 11, 2021 at 10:47 am
Sponsored Content by Huntington’s Disease Society of America It’s a rare genetic illness with no cure. Now you can help fund research and advocacy for the Huntington’s Disease ...
- Albany area organization focuses on Huntington's diseaseon May 11, 2021 at 7:34 am
Working with others in the region affected by this disease, in 2011, she started a local affiliate of Huntington’s Disease Society of America. "We started off with our first event and raised $16,000, ...
- Global Huntington's Disease Markets, Epidemiology and Patient Flow Report 2020-2035 - ResearchAndMarkets.comon May 10, 2021 at 9:03 pm
The "Global Huntington's Disease Epidemiology and Patient Flow - 2021" report has been added to ResearchAndMarkets.com's offering.
- Novel Small Molecule Targeting Huntington’s Disease Is Ready for Clinical Trialson May 9, 2021 at 9:00 pm
Bicoll GmbH has supported Galyan Bio Inc. in developing and optimizing an orally available small molecule for Huntington's Disease Target. Clinical trials are scheduled for 2022.Planegg, Germany - May ...
- Marathon Against Huntington’s Diseaseon May 9, 2021 at 9:00 pm
In 2015, my life changed forever when I tested positive for Huntington’s disease. As with so many others who suffer from this disease, denial gave way to sadness, sadness to anger, anger to ...
- Failure of Genetic Therapies for Huntington’s Devastates Communityon May 7, 2021 at 1:34 pm
Two pharmaceutical companies have halted clinical trials of gene-targeting therapies for Huntington’s disease (HD), following the drugs’ disappointing performance. Researchers had hoped that the ...
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