Efficacy of microneedle vaccine patches demonstrated | Vaccine … vaccinenewsdaily.com
The new patch can quicken drug delivery time while cutting waste
An assistant professor with the Virginia Tech – Wake Forest School of Biomedical Engineering has developed a flexible microneedle patch that allows drugs to be delivered directly and fully through the skin. The new patch can quicken drug delivery time while cutting waste, and can likely minimize side-effects in some cases, notable in vaccinations and cancer therapy.
News of the delivery technology was published in a recent issue of the scientific journal, Advanced Materials. Leading development of the flexible patch was Lissett Bickford, now an assistant professor and researcher of biomedical engineering and the mechanical engineering, both part of the Virginia Tech College of Engineering. Work on the technology was completed while Bickford was a post-doctoral research associate at the University of North Carolina Chapel Hill.
Microneedle patch technology used on the skin has existed for several years, each patch containing an array of hundreds of micron-sized needles that pierce the skin and dissolve, delivering embedded therapeutics. However, because of their rigid chemical makeup, the patches proved difficult in fully piercing into the skin, creating a waste of drug material and a slowed delivery time. Additionally, the patches also have been difficult to produce in bulk; typical fabrication procedures have required centrifugation.
Bickford, with her research team, including Chapel Hill graduate student Katherine A. Moga, were able to develop a new flexible microneedle patch that forms to the skin directly – think a regular household bandage – and then fully pierces the skin and dissolves. Bickford said the softer, more malleable and water-soluble material also allows for more precise control over the shape, size, and composition of the patch, with little to no waste.
The nanoparticle, micro-molding patch is based on Particle Replication In Non-wetting Templates (PRINT for short) technology, developed by University of North Carolina researcher and professor Joseph DeSimone. Unlike other methods for making these patches, the new technology allows for quicker and greater wide-scale production, reducing related costs.
The Latest Bing News on:
Microneedle patch
- ‘Lab on the skin’ can monitor several health statistics at once, in real timeon May 10, 2022 at 1:54 am
A new wearable gadget can monitor blood sugar and alcohol levels as well as muscle fatigue during workouts. The tiny monitor, which is about the size of a stack of six two pence coins, can be worn on ...
- You may soon be able to track how drunk you are on night out using microneedle patchon May 9, 2022 at 3:57 pm
Users will be able to view and track their levels on their phones. The microneedle patch is attached to a case of electronics that measures the different levels in the interstitial fluid using small ...
- New glucose monitor points the way to at-home medical labson May 9, 2022 at 2:24 pm
It’s called a “microneedle patch” — it’s placed on the body and its tiny pins just enter the skin to test interstitial fluid for glucose, alcohol and lactate. Will it be successful and make a ...
- New wearable patch gives precise detail about how your body is workingon May 9, 2022 at 10:09 am
A new wearable device can tell how much its owner has had to drink, how tired they are and more – all while fitting into a tiny circle on their arm. The new device, created by engineers at the ...
- Painless wearable gadget can measure blood sugar, alcohol and muscle fatigue at the SAME timeon May 9, 2022 at 9:01 am
According to the team, each microneedle patch is disposable, so customers could potentially buy in bulk and stock up when they need to when the device is commercialised. The wearable connects to ...
- Multi-tasking wearable continuously monitors glucose, alcohol, and lactateon May 9, 2022 at 8:01 am
Credit: Laboratory for Nanobioelectronics / UC San Diego The wearable consists of a microneedle patch connected to a case of electronics. Different enzymes on the tips of the microneedles react ...
- Multi-tasking wearable continuously monitors glucose, alcohol, and lactateon May 9, 2022 at 8:00 am
The wearable consists of a microneedle patch connected to a case of electronics. Different enzymes on the tips of the microneedles react with glucose, alcohol and lactate in interstitial fluid.
- This 3D Printed Vaccine Patch Is 10 Times as Effective as Arm Jabson May 3, 2022 at 5:00 pm
Related: Need a Cadaver for Medical School? 3D Printing to the Rescue Researchers at Stanford University and the University of North Carolina at Chapel Hill (UNC) collaborated on the microneedle patch ...
The Latest Google Headlines on:
Microneedle patch
The Latest Bing News on:
Microneedles
- Multi-Tasking Wearable Continuously Monitors Glucose, Alcohol, Lactateon May 13, 2022 at 11:10 am
The device is applied to the skin of the upper arm via microneedles smaller than the width of a human hair, which detect biomolecules in interstitial fluid; it is attached to a case housing the device ...
- Multi tasking wearable device to monitor glucose, alcohol, and lactate levelon May 12, 2022 at 9:30 pm
Engineers at the University of California San Diego have developed a prototype of such a wearable device that can continuously monitor several health stats-glucose, alcohol, and ...
- New Wearable Tracks Your Alcohol, Sugar, and Soreness Levels with Microneedleson May 9, 2022 at 10:39 am
While their coin-sized device has needles, the UC San Diego researchers used disposable microneedles, which are painless and minimally invasive, measuring about one-fifth the width of a human hair.
- New Wearable Tracks Your Alcohol, Sugar, and Soreness Levels with Microneedleson May 9, 2022 at 10:35 am
While their coin-sized device has needles, the UC San Diego researchers used disposable microneedles, which are painless and minimally invasive, measuring about one-fifth the width of a human hair.
