Scientists have developed an “intelligent knife” that can tell surgeons immediately whether the tissue they are cutting is cancerous or not.
In the first study to test the invention in the operating theatre, the “iKnife” diagnosed tissue samples from 91 patients with 100 per cent accuracy, instantly providing information that normally takes up to half an hour to reveal using laboratory tests.
The findings, by researchers at Imperial College London, are published today in the journal Science Translational Medicine. The study was funded by the National Institute for Health Research (NIHR) Imperial Biomedical Research Centre, the European Research Council and the Hungarian National Office for Research and Technology.
In cancers involving solid tumours, removal of the cancer in surgery is generally the best hope for treatment. The surgeon normally takes out the tumour with a margin of healthy tissue. However, it is often impossible to tell by sight which tissue is cancerous. One in five breast cancer patients who have surgery require a second operation to fully remove the cancer. In cases of uncertainty, the removed tissue is sent to a lab for examination while the patient remains under general anaesthetic.
The iKnife is based on electrosurgery, a technology invented in the 1920s that is commonly used today. Electrosurgical knives use an electrical current to rapidly heat tissue, cutting through it while minimising blood loss. In doing so, they vaporise the tissue, creating smoke that is normally sucked away by extraction systems.
The inventor of the iKnife, Dr Zoltan Takats of Imperial College London, realised that this smoke would be a rich source of biological information. To create the iKnife, he connected an electrosurgical knife to a mass spectrometer, an analytical instrument used to identify what chemicals are present in a sample. Different types of cell produce thousands of metabolites in different concentrations, so the profile of chemicals in a biological sample can reveal information about the state of that tissue.
In the new study, the researchers first used the iKnife to analyse tissue samples collected from 302 surgery patients, recording the characteristics of thousands of cancerous and non-cancerous tissues, including brain, lung, breast, stomach, colon and liver tumours to create a reference library. The iKnife works by matching its readings during surgery to the reference library to determine what type of tissue is being cut, giving a result in less than three seconds.
The technology was then transferred to the operating theatre to perform real-time analysis during surgery. In all 91 tests, the tissue type identified by the iKnife matched the post-operative diagnosis based on traditional methods.
The Latest Bing News on:
- Rian Johnson Reaches for Another Knifeon November 20, 2022 at 3:00 am
The writer-director discusses how Agatha Christie is misunderstood, the forthcoming sequel to “Knives Out,” and the life-changing screenwriting seminar that he attended with his dad.
- Suspected notorious criminal arrested in Nairobion November 20, 2022 at 12:04 am
The Directorate of Criminal Investigation team has nabbed a suspected mugger in Nairobi. On Saturday, police in Nairobi who were on patrol along Outering Road received intelligent reports that led to ...
- The Best Pocketknifeon November 18, 2022 at 3:59 am
The most important quality of any blade is its sharpness. It’s the primary determining factor in a knife’s performance and what makes a knife safe to use. A sharp knife requires less force ...
- Virginia man stopped at airport with knife 'artfully concealed' inside laptop: TSAon November 17, 2022 at 5:47 pm
A Virginia man was stopped at the airport after a watchful security agent spotted an "artfully concealed" double-bladed knife inside his laptop, the TSA said this week. The TSA agent initially ...
- TSA officers find ‘artfully concealed’ knife in traveler’s laptopon November 17, 2022 at 2:47 pm
(WRIC) – A traveler at Richmond International Airport in Virginia was stopped at a security checkpoint on Friday after officers with the Transportation Security Administration detected a knife ...
- How intelligent automation will change the way we workon November 17, 2022 at 11:30 am
Now organizations are turning to intelligent automation to automate key business processes to boost revenues, operate more efficiently, and deliver exceptional customer experiences. Intelligent ...
- Police seek ‘Rambo’-style knife in probe of Idaho student murders: reporton November 17, 2022 at 10:17 am
Police investigating the brutal slaughter of four University of Idaho students appear to be searching for a “Rambo”-style knife in the slayings, a local store owner said. Moscow Building ...
- Review: Benchmade Three-Piece Chef’s Knife Seton November 15, 2022 at 7:23 am
No special maintenance necessary. Easy to sharpen. I should say from the outset that I am generally opposed to knife sets, which typically include knives you don’t really need. In this case ...
- This 8-piece chef knife makes for a great present for your palson November 12, 2022 at 2:34 am
Learn more › In the kitchen, your knife is the extension of your hand. A sharp blade is crucial to prep work, allowing you to chop, slice, mince, and dice with relative ease. It’s no wonder ...
- The 6 best kitchen knife sets for carving turkeys and slicing pieon November 9, 2022 at 8:47 am
A good knife can really make or break your cooking game, as a dull knife can yield a slower prep-time at best and sliced fingers at worst. Plus, with Thanksgiving feasts just around the corner ...
The Latest Google Headlines on:
[google_news title=”” keyword=”Intelligent knife” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]
The Latest Bing News on:
Fix the internet
- Tesla Model Y And Model 3 Recall Covers 321,000 EVs, But The Fix Is Simpleon November 20, 2022 at 6:11 pm
Tesla is back with yet another recall for November 2022, one described as rare but that could increase the risk of accidents while on the road.
- To expand broadband, fix utility pole ruleson November 20, 2022 at 5:13 am
Lawmakers need to ensure that funding to expand broadband connectivity is used to its fullest potential by expediting access to utility poles.
- The Nest Wifi Pro is great but I'm returning it — here's whyon November 20, 2022 at 12:01 am
I’ve always wanted to test out one of the search giant’s routers but the Nest Wifi didn’t seem worth it a few months ago due to its aging hardware. Plus, I picked up the TP-Link Deco XE75 with Wi-Fi ...
- How to Fix the "IPv4/IPv6 No Internet Access" Error on Windowson November 19, 2022 at 8:15 am
There are a few reasons why Windows will give you the "IPv4/IPv6 No Internet Access" error, so here are some easy fixes you can try.
- The long-awaited US broadband internet maps are here — for you to challengeon November 19, 2022 at 4:14 am
What’s wrong with US broadband? This is a map of America’s broadband problem In 2021, we need to fix America’s internet Today, the FCC has finally put the first “pre-production draft” version of its ...
- Black Screen on FFXIV Launcher: 5 Ways to Fix Iton November 18, 2022 at 10:00 pm
You can easily resolve the black screen issue with the FFXIV launcher by adding the game to the exception list of your antivirus.
- Fix toys, arcade machines and even your own home in the next game from the creator of PC Building Simulatoron November 17, 2022 at 11:30 am
It’s the next game by Claudiu Kiss, the creator of PC Building Simulator, though it has swapped motherboards for floorboards, benchmarking for an actual workbench, and graphics cards for vintage games ...
- The Easiest Ways To Fix A PS5 That Won't Connect To Wi-Fion November 16, 2022 at 1:16 pm
If your Playstation 5 won't connect to the internet or your Wi-Fi we have some quick and easy suggestions that might help get you back to your gaming.
- There’s Another Aftermarket Fix for the Big BMW M4 Grilleon November 13, 2022 at 1:15 pm
ADRO offers a bumper kit that fixes the kidney grille design on the BMW M4 and it's far better looking than the stock bumper.
- Google’s rolling out a Nest Wifi Pro update to fix slow internet speedson November 12, 2022 at 3:01 pm
Google says it’s rolling out a software update for the new Nest Wifi Pro early next week to address the slow internet speeds experienced by some users. In a statement to The Verge, Sanjay Noronha, ...
The Latest Google Headlines on:
Fix the internet
[google_news title=”” keyword=”fix the internet” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]