The world’s food supply got a little more plentiful thanks to a scientific breakthrough.
Eduard Akhunov, associate professor of plant pathology at Kansas State University, and his colleague, Jorge Dubcovsky from the University of California-Davis, led a research project that identified a gene that gives wheat plants resistance to one of the most deadly races of the wheat stem rust pathogen — called Ug99 — that was first discovered in Uganda in 1999. The discovery may help scientists develop new wheat varieties and strategies that protect the world’s food crops against the wheat stem rust pathogen that is spreading from Africa to the breadbaskets of Asia and can cause significant crop losses.
Other Kansas State University researchers include Harold Trick, professor of plant pathology; Andres Salcedo, doctoral candidate in genetics; and Cyrille Saintenac, a postdoctoral research associate currently working at the Institut National de la Recherche Agronomique in France. The project was funded by the U.S. Department of Agriculture and Borlaug Global Rust Initiative.
The team’s study, “Identification of Wheat Gene Sr35 that Confers Resistance to Ug99 Stem Rust Race Group,” appears in the journal Science.
It identifies the stem rust resistance gene named Sr35, and appears alongside a study from an Australian group that identifies another effective resistance gene called Sr33.
“This gene, Sr35, functions as a key component of plants’ immune system,” Akhunov said. “It recognizes the invading pathogen and triggers a response in the plant to fight the disease.”
Wheat stem rust is caused by a fungal pathogen. According to Akhunov, since the 1950s wheat breeders have been able to develop wheat varieties that are largely resistant to this pathogen. However, the emergence of strain Ug99 in Uganda in 1999 devastated crops and has spread to Kenya, Ethiopia, Sudan and Yemen, though has yet to reach the U.S.
“Until that point, wheat breeders had two or three genes that were so efficient against stem rust for decades that this disease wasn’t the biggest concern,” Akhunov said. “However, the discovery of the Ug99 race of pathogen showed that changes in the virulence of existing pathogen races can become a huge problem.”
As a first line of defense, wheat breeders and researchers began looking for resistance genes among those that had already been discovered in the existing germplasm repositories, he said.
“The Sr35 gene was one of those genes that was discovered in einkorn wheat grown in Turkey,” Akhunov said. “Until now, however, we did not know what kind of gene confers resistance to Ug99 in this wheat accession.”
To identify the resistance gene Sr35, the team turned to einkorn wheat that is known to be resistant to the Ug99 fungal strain. Einkorn wheat has limited economic value and is cultivated in small areas of the Mediterranean region. It has been replaced by higher yielding pasta and bread wheat varieties.
Researchers spent nearly four years trying to identify the location of the Sr35 gene in the wheat genome, which contains nearly two times more genetic information than the human genome.
Once the researchers narrowed the list of candidate genes, they used two complimentary approaches to find the Sr35 gene. First, they chemically mutagenized the resistant accession of wheat to identify plants that become susceptible to the stem rust pathogen.
“It was a matter of knocking out each candidate gene until we found the one that made a plant susceptible,” Akhunov said. “It was a tedious process and took a lot of time, but it was worth the effort.”
The Latest Bing News on:
- E. coli bacteria is more capable of developing antibiotic resistance: Studyon November 26, 2023 at 9:31 am
According to a recent study published in Science, E. coli bacteria may be far more capable of developing antibiotic resistance than previously thought.
- New 'gene therapy' can treat rare, hereditary diseases with no cureon November 25, 2023 at 10:27 pm
The researchers used the mini-organs, such as mini-brains, mini-lungs and mini-eyes, which Bjoras's team has been working on growing since 2018, to.Health. healthcare. wellness. well-being. fitness.
- E. coli bacteria more capable at evolving antibiotic resistance than previously thoughton November 25, 2023 at 10:11 am
E. coli bacteria may be far more capable at evolving antibiotic resistance than scientists previously thought, according to a new study. Led by the Santa Fe Institute’s external professor Andreas ...
- Science For Everyone: How Antimicrobial Resistance Impacts Agriculture, Its Effect On Humans, And What Must Be Doneon November 25, 2023 at 7:26 am
This week, in ABP Live's science column, we explain the impact of antimicrobial resistance on livestock and plant agriculture, how this affects humans, and what must be done to combat the threat.
- ‘Over aeons, an arms race grew between plants and insects — it also caused pesticide resistance’on November 24, 2023 at 2:29 pm
The relationship between plants and insects is generally considered peaceful however, can you share your insights on how butterflies protect themselves from dangers plants pose to ...
- A Concerning Link Between Malnutrition & Antibiotic Resistance is Discoveredon November 24, 2023 at 8:26 am
Humans and most animals host a community of microbes, including bacteria, fungi, and viruses, in their gastrointestinal tracts. | Microbiology ...
- Gene therapy could reverse symptoms of rare, hereditary DOOR syndromeon November 23, 2023 at 3:59 pm
A lot of research has been done over many decades on diseases that are widespread in large parts of the population, such as cancer and heart disease. As a result, treatment methods have improved ...
- Curbing pharmaceutical effluent pollution: A crucial step in fighting antimicrobial resistanceon November 23, 2023 at 8:34 am
Antimicrobial resistance (AMR) is a growing global threat, especially in low- and middle-income countries (LMICs), causing prolonged illnesses, heightened antimicrobial use, increased healthcare ...
- The digital technology helping clinicians and researchers tackle antimicrobial resistanceon November 22, 2023 at 12:26 pm
Science X is a network of high quality websites with most complete and comprehensive daily coverage of the full sweep of science, technology, and medicine news ...
- 🔒 Nowhere to hide from drug resistant super bugs – latest findon November 21, 2023 at 1:39 pm
Researchers find a gene first discovered in bacteria from India 8,000 miles away in the Arctic, raising fears about global reach antibiotic-resistant bugs.
The Latest Google Headlines on:
[google_news title=”” keyword=”Resistance gene” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]
The Latest Bing News on:
- GENE HUANG, Ph.D.on November 22, 2023 at 7:12 pm
Gene Huang, Ph.D., is vice president, chief economist. He joined Abbott in this role in September 2013. Prior to joining Abbott, Dr. Huang was Chief Economist and a Vice President at FedEx. Dr. Huang ...
- Gene Therapy Newson November 20, 2023 at 4:00 pm
Oct. 31, 2023 — Individuals living with severe sickle cell disease (SCD) are highly interested in new, potentially curative gene therapy treatments and are willing ... Aug. 11, 2023 ...
- Researchers use quantum computing to predict gene relationshipson November 19, 2023 at 4:00 pm
Their project used the new computing technology to map gene regulatory networks (GRNs), which provide information about how genes can cause each other to activate or deactivate. "The GRN is like a ...
- Novel approaches for correcting gene expression insufficiencyon November 16, 2023 at 4:00 pm
Messenger RNA, or mRNA, contains instructions for DNA to produce proteins. Many diseases, including cancer and many genetic disorders, result from insufficient gene—and therefore protein ...
- World's first gene therapy for sickle cell and thalassemia approved in the U.K.on November 16, 2023 at 8:51 am
"The future of life-changing cures resides in CRISPR based (gene-editing) technology," said Dr. Helen O'Neill of University College London. "The use of the word 'cure' in relation to sickle cell ...
- Patient Dies After Being Gene-Edited to Have Lower Cholesterolon November 15, 2023 at 4:00 pm
Researchers have been able to reduce dramatically the level of bad cholesterol in human subjects after injecting them with an experimental gene editing treatment, according to the science journal ...
- Gene Therapyon November 12, 2023 at 3:59 pm
Forge Biologics operates a contract manufacturing business and develops its own gene therapies, which appears to have attracted the Japan-based food and biotechnology company. Rapid scientific ...
- Gene Markson November 11, 2023 at 4:00 pm
I am a Certified Public Accountant and run a 10 person technology and financial management consulting firm. I speak 50+ times per year to business groups on technology, the economy, public policy ...
- New Gene Editing Treatment Cuts Dangerous Cholesterol in Small Studyon November 11, 2023 at 4:00 pm
So they volunteered for an experimental cholesterol-lowering treatment using gene editing that was unlike anything tried in patients before. The result, reported Sunday by the company Verve ...
- Gene regulation articles from across Nature Portfolioon November 1, 2023 at 5:00 pm
Gene regulation refers to the mechanisms that act to induce or repress the expression of a gene. These include structural and chemical changes to the genetic material, binding of proteins to ...
The Latest Google Headlines on:
[google_news title=”” keyword=”Sr35 gene” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]