B0007267 Muscle Fibers Credit: Ivor Mason, KCL. Wellcome Images
Using stem cells, U of M researchers have found a way to regenerate muscles in diseased lab mice.
It’s being called breakthrough research by medical journals around the world, and it’s happening at the University of Minnesota.
Using stem cells, U of M researchers have found a way to regenerate muscles in diseased lab mice.
They hope this breakthrough will lead to better treatments for patients fighting Duchenne Muscular Dystrophy, which brings with it learning disabilities, and extreme fatigue.
Researchers were able to essentially correct the gene mutation that causes muscular dystrophy.
Dr. Rita Perlingeiro heads the lab conducting the study. She explains the first step is to remove skin cells from the tail of a mouse with the disease.
“These are skin, simply skin,” she said. “They don’t make muscle.”
Using a molecularly engineered protein, researchers reprogram the cell to make any tissue in the animal’s body.
Next researchers corrected the disease in the reprogrammed cell, and reprogrammed them once again — this time to be muscle stem cells.
“The next step is we specifically instruct them to make skeletal muscle,” she said.
Researchers then measured the results using a device that quantifies muscle function. While the mice weren’t cured, they were able to restore some mobility.
Perlingeiro says there are still many steps to go through before bringing this to humans.
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Regenerate Muscles
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The Latest Bing News on:
Muscle regeneration
- Study: Metabolic switch may regenerate heart muscle following heart attackon April 16, 2021 at 6:18 am
Research from the University of Wisconsin–Madison finds that a new therapeutic approach for heart failure could help restore cardiac function by regenerating heart muscle. In a study recently ...
- UNIVERSITY of WISCONSIN–MADISON: Metabolic switch may regenerate heart muscle following heart attackon April 15, 2021 at 11:06 pm
Research from the University of Wisconsin–Madison finds that a new therapeutic approach for heart failure could help restore cardiac function by regenerating heart muscle.In a study recently published ...
- UW-Madison: Metabolic switch may regenerate heart muscle following heart attackon April 15, 2021 at 3:10 pm
MADISON – Research from the University of Wisconsin-Madison finds that a new therapeutic approach for heart failure could help restore cardiac function by regenerating heart muscle. In a study ...
- Metabolic switch may regenerate heart muscle following heart attackon April 15, 2021 at 7:26 am
Research from the University of Wisconsin-Madison finds that a new therapeutic approach for heart failure could help restore cardiac function ...
- BioAge picks up muscle-aging program from Amgen, bringing pipeline count to 3on April 14, 2021 at 4:00 am
Dray and his team have helped BioAge test BGE-105 in mouse models of muscle regeneration under a materials transfer agreement with Amgen ahead of the licensing deal. BioAge found the drug through its ...
- Heart attack: How can we regenerate damaged tissue?on April 13, 2021 at 6:25 am
After injury, zebra fish can regrow heart tissue. A new study investigates the mechanisms and asks whether we could use this knowledge to treat humans.
- Secret genetic switch in zebrafish key to heart regenerationon April 12, 2021 at 4:40 pm
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- Astonishing Secret Switch Discovered That Could Revolutionize Heart Attack Treatmenton April 10, 2021 at 12:39 am
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