via Phys.org
Max Planck scientists have used silk from the tasar silkworm as a scaffold for heart tissue.
Damaged human heart muscle cannot be regenerated. Scar tissue grows in place of the damaged muscle cells. Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim are seeking to restore complete cardiac function with the help of artificial cardiac tissue. They have succeeded in loading cardiac muscle cells onto a three-dimensional scaffold, created using the silk produced by a tropical silkworm.
Of all the body’s organs, the human heart is probably the one most primed for performance and efficiency. Decade after decade, it continues to pump blood around our bodies. However, this performance optimisation comes at a high price: over the course of evolution, almost all of the body’s own regeneration mechanisms in the heart have become deactivated. As a result, a heart attack is a very serious event for patients; dead cardiac cells are irretrievably lost. The consequence of this is a permanent deterioration in the heart’s pumping power and in the patient’s quality of life.
In their attempt to develop a treatment for the repair of cardiac tissue, scientists are pursuing the aim of growing replacement tissue in the laboratory, which could then be used to produce replacement patches for the repair of damaged cardiac muscle. The reconstruction of a three-dimensional structure poses a challenge here. Experiments have already been carried out with many different materials that could provide a scaffold substance for the loading of cardiac muscle cells.
“Whether natural or artificial in origin, all of the tested fibres had serious disadvantages,” says Felix Engel, Research Group Leader at the Max Planck Institute for Heart and Lung Research in Bad Nauheim. “They were either too brittle, were attacked by the immune system or did not enable the heart muscle cells to adhere correctly to the fibres.” However, the scientists have now found a possible solution in Kharagpur, India.
The Latest Bing News on:
Artificial cardiac tissue
- Artificial Valve Market Size and Share 2022 Analysis by Trends, Growth Factor, Development and Forecast to 2028 Research Reporton May 11, 2022 at 4:08 am
May 11, 2022 (The Expresswire) -- "Final Report will add the analysis of the impact of COVID-19 on this industry." “Artificial Valve Market” 2022 ...
- How to prevent the heart from sticking to other organs after surgeryon May 9, 2022 at 8:07 am
had an artificial valve installed in his heart. But the first surgery didn’t go very well. And when the surgical team re-operated on his body to fix it they ran into a layer of scar tissue that they ...
- Permanent Artificial Hearts: Long-Sought Replacements May Not Be Far Awayon May 7, 2022 at 4:59 pm
A permanent implantable artificial heart has long been a goal of medicine ... The heart is a four-chambered pump made from specialized muscle tissue. The upper chambers are referred to as the ...
- A Bold New World: GE Healthcare's Pioneering Deep Learning Image Reconstruction Technology Benefits More Than 2 Million Patients Globallyon May 6, 2022 at 11:23 am
Artificial intelligence (AI) and healthcare access remain key themes at ISMRM as researchers and clinicians seek more efficient and effective solutions in today's resource-constrained environment GE H ...
- Miniature heart replica could help optimize cardiac disease treatmentson May 5, 2022 at 9:00 am
A living cardiac pump-on-a-chip could help researchers study how the heart works and investigate new treatments for heart disease ...
- Cardiovascular Devices Market Size Worth $76.52Bn, Globally, By 2028 At 6.9% CAGR - Exclusive Report By The Insight Partners'on May 4, 2022 at 3:43 am
and Geography Artificial Tissue Heart Valve Market Forecast to 2028 - COVID-19 Impact and Global Analysis By Type (Transcatheter Heart Valve, Surgical Heart Valve); Application (Aortic Stenosis ...
- Cardiovascular Devices Market Size Worth $76.52Bn, Globally, by 2028 at 6.9% CAGR - Exclusive Report by The Insight Partnerson May 4, 2022 at 2:30 am
and Geography Artificial Tissue Heart Valve Market Forecast to 2028 - COVID-19 Impact and Global Analysis By Type (Transcatheter Heart Valve, Surgical Heart Valve); Application (Aortic Stenosis, ...
- AI Technology Can Predict Life-Threatening Heart Trouble, Researchers Sayon May 2, 2022 at 6:00 pm
Researchers at Johns Hopkins University developed artificial intelligence technology ... its kind and works by analyzing scar tissue in a patient’s heart, which detects patterns invisible ...
- Why artificial intelligence will be key to NHS workforce and waiting times challengeson April 27, 2022 at 11:03 pm
There is arguably no greater opportunity than in transformative artificial intelligence (AI ... at what it does and undoubtedly lies at the heart of key NHS aims going forward, supporting ...
The Latest Google Headlines on:
Artificial cardiac tissue
The Latest Bing News on:
Replacement heart tissue
- Designer neurons offer new hope for treatment of Parkinson's diseaseon May 11, 2022 at 12:21 pm
Neurodegenerative diseases damage and destroy neurons, ravaging both mental and physical health. Parkinson's disease, which affects over 10 million people worldwide, is no exception. The most obvious ...
- New minimally invasive treatments offer hope for patients with severe heart valve diseaseon May 11, 2022 at 8:28 am
The procedure involves inserting 2 bioprosthetic (tissue) valves known as the TricValve into the large veins close to the heart, without the need to remove the defective tricuspid valve.
- New minimally invasive treatments offered in NHCS offer hope for patients with severe heart valve diseaseon May 10, 2022 at 11:47 pm
National Heart Centre Singapore (NHCS) now offers two new procedures – TricValve® and TriClipTM - bringing a comprehensive suite of treatment options, ranging from medication therapies, minimally ...
- Joint health is crucial for women’s healthon May 9, 2022 at 9:49 pm
Measuring joint health is difficult, but biomarkers could help identify temporary and longer-term cartilage and joint issues that some supplement ingredients may aid.
- Humacyte to Provide Human Acellular Vessels(TM) (HAVs(TM)) to Front-line Hospitals in Ukraine for Treatment of Vascular Trauma Injurieson May 9, 2022 at 7:31 am
HAVs are engineered, off-the-shelf replacement vessels being developed ... in coronary artery bypass grafts, pediatric heart surgery, treatment of type 1 diabetes, and multiple novel cell and tissue ...
- Humacyte to Provide Human Acellular Vessels™ (HAVs™) to Front-line Hospitals in Ukraine for Treatment of Vascular Trauma Injurieson May 8, 2022 at 10:00 pm
First shipment of HAVs to six Ukrainian hospitals made today -- -- Product candidate to be used for civilian and military vascular trauma repair, the HAV’s lead investigational indication -- DURHAM, N ...
- $2M Grant to Speed PolyVascular’s Pediatric Catheter-Delivered Pulmonary Valve Replacement to Marketon May 4, 2022 at 5:01 pm
Edwards Sapien XT also delivers a valve replacement device through catheter. Both devices use animal tissue within a metal frame. PolyVascular identified the pediatric heart valve space based on ...
- Scar treatment has many benefitson May 2, 2022 at 9:00 pm
James Pearce was naturally unnerved when he had to undergo open heart surgery ... who’ve had joint replacement suffer from range of motion limitations due to scar tissue.
- “I felt invincible – then I needed heart surgery in my fifties.”on May 2, 2022 at 6:01 am
This one revealed that his heart muscle had become enlarged ... including weighing up the pros and cons of having a tissue or mechanical replacement valve. He broke the process down into smaller steps ...
- KU hospital upbeat after its first open heart surgerieson April 28, 2022 at 1:00 pm
Two women are the first Kenyans to undergo open heart surgery at Kenyatta University and Teaching Hospital. The surgeries were done this week, making KU hospital the third public facility after ...
The Latest Google Headlines on:
Replacement heart tissue