Patients not receiving statins were almost twice as likely to die
Statins, traditionally known as cholesterol-lowering drugs, may reduce mortality among patients hospitalized with influenza, according to a new study released online by The Journal of Infectious Diseases.
It is the first published observational study to evaluate the relationship between statin use and mortality in hospitalized patients with laboratory-confirmed influenza virus infection, according to Vanderbilt’s William Schaffner, M.D., professor and chair of Preventive Medicine.
“We may be able to combine statins with antiviral drugs to provide better treatment for patients seriously ill with influenza,” said Schaffner, who co-authored the study led by Meredith Vandermeer, MPH, of the Oregon Public Health Division.
Researchers studied adults who were hospitalized with laboratory-confirmed influenza from 2007-2008 to evaluate the association between patients who were prescribed statins and influenza-related deaths.
Among 3,043 hospitalized patients with laboratory-confirmed influenza, 33 percent were given statin medications prior to or during hospitalization. After adjusting for various factors, researchers found that patients not receiving statins were almost twice as likely to die from influenza as those who received the medication.
Read more . . .